ArticleBMC public health2025
Global, regional, and national trends in maternal hemorrhage, 1992-2021: a hierarchical cluster and age-period-cohort analysis of the Global Burden of Disease Study 2021 and projections to 2036.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Comparative analysis of early-onset and late-onset esophageal cancer burden in China, 1990-2021: based on the 2021 Global Burden of Disease Study.Esophagus : official journal of the Japan Esophageal Society · 2026Article
- Prediction of Postpartum Haemorrhage After Labour Induction: An Internally Validated 10-Hour Risk-Stratification Threshold.Diagnostics (Basel, Switzerland) · 2026Article
- Global, regional and national burden of maternal haemorrhage (2000-2021) and projections to 2050 in 204 countries and territories.BMJ open · 2026Article
- Regional inequalities and temporal trends in maternal disorders across sub-Saharan Africa, 1990-2023: a systematic analysis of the global burden of disease 2023 data.Archives of public health = Archives belges de sante publique · 2026Article
- Long-term trends in disease burden of esophageal cancer in China and the forecast until 2050.BMC gastroenterology · 2026Article
- Trends in otitis media burden among BRICS from 1990 to 2023 and projections to 2040: an age-period-cohort analysis based on the 2023 global burden of disease study.Italian journal of pediatrics · 2026Article
- Global and Regional Impact of Pelvic Inflammatory Disease in Females Across All Age Groups (1990-2021) with Projections to 2046: Findings from the 2021 Global Burden of Disease Study.International journal of women's health · 2026Article
- An Analysis of Trends in the Burden of Maternal Hemorrhage Attributable to Iron Deficiency in China from 1990 to 2023: A Population-Based Study.International journal of women's health · 2026Article
- Global burden and epidemiological determinants of pulmonary arterial hypertension among women aged 55 years and older: a GBD 2023 analysis.Frontiers in medicine · 2026Article
- Cell Salvage in the Management of Postpartum Hemorrhage: A Comprehensive Review of the Current Literature.Cureus · 2025Review
- Global burden, disparities, and determinants of postpartum haemorrhage among women who gave birth: an umbrella review of systematic reviews and meta-analyses.Frontiers in reproductive health · 2025Review
- Editorial: Use of artificial intelligence to improve maternal and neonatal health in low-resource settings.Frontiers in global women's health · 2025Article
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6 authors.
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Abstract
backgroundMaternal hemorrhage (MH) remains a leading cause of maternal morbidity and mortality worldwide. Understanding global trends and future projections is essential for informing effective health strategies.
methodsThis study drew on data from the Global Burden of Disease (GBD) 2021 study and applied hierarchical cluster analysis, the age-period-cohort (APC) model, and the Bayesian age-period-cohort (BAPC) model to assess MH incidence, age-standardized incidence rates (ASIRs), and net drift from 1992 to 2021, as well as to forecast trends through 2036.
resultsFrom 1992 to 2021, the global annual incidence of MH modestly increased from 13,847,163 to 13,914,838 cases. Despite this, the ASIR decreased from 948.07 to 722.16 per 100,000 people, with a net drift of -0.83 (95% uncertainty intervals (UIs): -1.03 to -0.64), indicating a reduction in risk, especially in low and low-middle socio-demographic index (SDI) regions. Persistent challenges remain in certain Sub-Saharan Africa countries, Eastern Europe, and East Asia. Saudi Arabia has made significant progress in managing and preventing MH. According to APC model analyses, women aged 20-29 are at the highest risk, although improvements have been observed since 2002, with decreasing risks in subsequent generations. BAPC model projections suggest that by 2036, the number of global MH cases will reduce to 10,287,971, with an expected ASIR of 479.83 per 100,000 people (95% UI: 479.82 to 479.83).
conclusionsAlthough global MH burden has decreased, substantial disparities persist across regions and age groups. Targeted public health efforts are needed, particularly in Europe, East Asia, parts of Sub-Saharan Africa, and among women aged 20-29, to further mitigate the impact of MH.
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