Evidence map›Paper›PMID 40707841›Full record

Trial reportJournal of gastrointestinal cancer2025

"Impact of Limberg Flap Reconstruction Following Abdominoperineal Resection: A Randomized Controlled Trial."

Mina Alvandipour, Sohrab Sayyadi, Nasibeh Samarghandi, Asal Khodabakhsh, Atousa Mortazavi Milani, Mohammad Javad Najafi

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of gastrointestinal cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mina AlvandipourDepartment of Surgery, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Sohrab SayyadiDepartment of Surgery, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Nasibeh SamarghandiDepartment of Surgery, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Asal KhodabakhshStudent Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
Atousa Mortazavi MilaniDepartment of Gynecology and Obstetrics, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Mohammad Javad NajafiDepartment of Surgery, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. mjnajafi@rocketmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerineal wound complications after abdominoperineal resection (APR) for low rectal cancer remain a significant challenge. Effective reconstruction methods are critical to reducing morbidity and improving outcomes.

objectiveTo compare the effectiveness of primary closure versus Limberg flap reconstruction in managing perineal defects post-abdominoperineal resection.

methodsSixty patients undergoing APR for rectal cancer were randomized into two groups. Fifty-four patients completed the study and were analyzed (26 in the primary closure group and 28 in the Limberg flap group). Baseline characteristics, including mean age, gender distribution, cancer stage, and neoadjuvant chemoradiation status, were recorded. Primary outcomes included uncomplicated wound healing, while secondary outcomes assessed complications, wound healing time, and hospital stay. Statistical significance was set at p < 0.05.

resultsThe average age of the participants was 68.04 ± 11.50 years, with an average weight of 74.42 ± 12.47 kg and a mean Body Mass Index (BMI) of 27.31 ± 3.90 kg/m

conclusionLimberg flap reconstruction offers superior outcomes compared to primary closure for perineal reconstruction following APR.

Indexed as

PerineumPlastic Surgery ProceduresProctectomyRectal NeoplasmsSurgical FlapsAgedFemaleHumansLength of StayMaleMiddle AgedNeoadjuvant TherapyPostoperative ComplicationsTreatment OutcomeWound HealingAbdominoperineal resectionLimberg flapPerineal wound healingPostoperative complicationsRandomized controlled trialWound closure techniques

Identifiers

PMID40707841

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.