ArticleCardiovascular and interventional radiology2025
Road to Genicular Artery Embolization: Importance of the Anastomotic Network.
Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Outcome and Safety of Genicular Artery Embolization for Knee Osteoarthritis: A Systematic Review and Meta-Analysis.Cardiovascular and interventional radiology · 2026Pooled it
- Commentary: Genicular Artery Embolization using Imipenem/Cilastatin vs. Microsphere for Knee Osteoarthritis (GAUCHO): 12-Month Clinical Results of a Single-blind Randomized Controlled Trial.Cardiovascular and interventional radiology · 2026Article
- Genicular Artery Embolization for Chronic Knee Pain: Expert Consensus Recommendations on Indications, Technique and Clinical Care Using a Delphi Process.Cardiovascular and interventional radiology · 2026Article
- Repeated Genicular Artery Embolization Using Permanent Microspheres for Severe Osteoarthritis and Postsurgical Pain.Cardiovascular and interventional radiology · 2026Observational
- Segmentation of blush size guides embolic endpoints in genicular artery embolization.European radiology · 2026Article
- Vascular Complication After Revision of Total Knee Arthroplasty (R-TKA): A Case of Popliteal Branch Pseudoaneurysm Successfully Treated with Embolization-A Case Report and Mini Review of the Literature.Journal of clinical medicine · 2026Article
- Genicular artery embolization in a patient with popliteal artery agenesis: a case report.CVIR endovascular · 2025Article
- Transarterial Microembolization in Tendinopathies: From Experimental to Evidence-Based Therapy.Cardiovascular and interventional radiology · 2025Article
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Authors and funding
10 authors.
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Abstract
purposeTo explore feasibility, safety, perfusion changes and clinical outcomes following retrograde genicular artery embolization (R-GAE). MATERIALS AND
methodsThis prospective exploratory study assessed the technical approach, perfusion changes and clinical outcomes after R-GAE. Anastomoses between genicular arteries (GA) were evaluated during angiography. Technical success was defined as retrograde opacification of GA via anastomoses up to their origin, followed by embolization. Remaining GA were embolized antegrade (A-GAE), and additional A-GAE was performed after R-GAE (A-/R-GAE) if feasible. Time-density curves calculated peak intensity (PI), time-to-arrival (TTA), and area under the curve (AUC). Clinical outcomes were assessed using the knee injury and osteoarthritis outcome score (KOOS) at 6 weeks, 3 and 6 months. No comparison between R-GAE and A-GAE was performed.
resultsA total of 132 vessels were embolized in 35 patients: 73 A-GAE, 39 R-GAE, and 20 A-/R-GAE. Technical success was achieved in all patients, with six cases of mild, transient skin discoloration. All KOOS subscales showed significant improvement at all time points (p < 0.05). No significant changes in PI, TTA, or AUC were observed in the parent vessels or anastomoses after GAE. Target vessels demonstrated reduced AUC (542.6 vs. 253.1; p < 0.01) and PI (110.3 vs. 51.2; p < 0.01), with increased TTA (7.1 s vs. 11.2 s; p < 0.01). Antegrade angiography after R-GAE revealed residual blush in all patients, requiring additional A-GAE.
conclusionR-GAE is a safe and feasible catheterization route with potential efficacy at early follow-up. Perfusion areas reached by R-GAE may differ from A-GAE highlighting the anastomotic network's impact on hemodynamics during GAE.
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