ArticleEndocrine2025
Sleep disorders in patients with differentiated thyroid cancer: a case-control study.
Article in Endocrine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Return to Work and Employment Outcomes in Survivors of Differentiated Thyroid Cancer: A Systematic Review.Journal of occupational rehabilitation · 2026Pooled it
- Factors Associated with Sleep Disruption and Fatigue in Thyroid Cancer Survivors.Current oncology (Toronto, Ont.) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectiveThyroid cancer survivors are prone to sleep disorders. This study aims to compare the differences of sleep quality between patients with differentiated thyroid cancer (DTC) and healthy controls, as well as to investigate the risk factors for sleep disorders in DTC survivors.
methodsA case-control study was conducted. The Pittsburgh Sleep Quality Index (PSQI) was utilized to assess sleep quality, the Self-rating Anxiety Scale (SAS) to evaluate anxiety, and the Self-rating Depression Scale (SDS) to measure depression. Chi-square tests and Mann-Whitney tests were employed to identify differences between DTC patients and healthy controls. Univariate and multivariate logistic regression analyses were conducted to explore the independent risk factors for sleep disorders in DTC patients.
resultsA total of 318 DTC patients and 72 healthy controls were included. Sleep disorders were prevalent, affecting 50.3% of DTC patients compared to 34.7% of healthy controls, with a significant difference noted (P = 0.017). Notable disparities were observed in sleep disturbances (P = 0.031) and daytime dysfunction (P = 0.019). Furthermore, employment status (P = 0.026), anxiety (P < 0.001), and depression (P = 0.001) were identified as independent predictors of sleep disorders in DTC patients.
conclusionsDTC patients are susceptible to sleep disorders, the prevalence was as high as 50.3%. Clinicians should be vigilant in identifying DTC patients who are unemployed or experiencing anxiety or depression, as these factors significantly influence sleep quality. Clinicians should offer these patients appropriate support and interventions, such as disease information support and multidisciplinary consultations, to enhance their overall well-being and quality of life.
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Registered trials
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