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ArticleScientific reports2025

Association of impaired pulmonary function and objectively measured physical activity in a population study.

Maria Lopmeri, Tiina Mattila, Kari Tokola, Tommi Vasankari, Tuija Jääskeläinen, Jouni Lahti, Tuula Vasankari

Registry-linked trialAbstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07575841 (Comparative Efficacy of a Supervised Pulmonary Rehabilitation Program Performed 3 Days/Week Versus 1 Day/Week in Patients With Chronic Obstructive Pulmonary Disease), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07575841 nanot yet recruitingnot on this mapstarted 2027, after this paper: background citation

Comparative Efficacy of a Supervised Pulmonary Rehabilitation Program Performed 3 Days/Week Versus 1 Day/Week in Patients With Chronic Obstructive Pulmonary Disease (COPD): a Randomized Clinical Trial

TypeinterventionalSponsorHospital Universitario Fundación AlcorcónRan2027 to 2028Enrolled158ConditionsCOPD, COPD (Chronic Obstructive Pulmonary Disease)ArmsPulmonary Rehabilitation
3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Maria LopmeriDepartment of Pulmonary Diseases, Heart and Lung Center, Helsinki University Hospital and University of Helsinki, Meilahti Triangle Hospital, 6th floor, PO Box 372, 00029 HUS, Helsinki, Finland. maria.lopmeri@helsinki.fi.
Tiina MattilaDepartment of Pulmonary Diseases, Heart and Lung Center, Helsinki University Hospital and University of Helsinki, Meilahti Triangle Hospital, 6th floor, PO Box 372, 00029 HUS, Helsinki, Finland.
Kari TokolaThe UKK Institute for Health Promotion Research, Kaupinpuistonkatu 1, 33500, Tampere, Finland.
Tommi VasankariThe UKK Institute for Health Promotion Research, Kaupinpuistonkatu 1, 33500, Tampere, Finland.
Tuija JääskeläinenFinnish Institute for Health and Welfare, Mannerheimintie 166, 00271, Helsinki, Finland.
Jouni LahtiFinnish Institute for Health and Welfare, Mannerheimintie 166, 00271, Helsinki, Finland.
Tuula VasankariFinnish Lung Health Association (FILHA), Filha Ry, Sibeliuksenkatu 11 A 1, 00250, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to modern lifestyles, physical activity (PA) has decreased at a population level, resulting in health concerns worldwide. Increased level of PA can reduce mortality and morbidity in pulmonary diseases, such as asthma and chronic obstructive pulmonary disease (COPD). Many previous studies on the association between pulmonary function and PA assessed PA by questionnaires. We aimed to study the cross-sectional association between pulmonary function and objectively measured PA and sedentary behavior (SB) in population-based data. A total of 4729 subjects participated in the Health 2011 survey, which represents the Finnish adult population. Of these, 1511 completed spirometry and the required 4-day accelerometer wear time. Spirometry values of forced expiratory volume in 1s (FEV1) and forced vital capacity (FVC) were determined. We compared the differences in daily PA measured with triaxial accelerometer between those with obstructive or restrictive spirometry results (defined as FEV1/FVC < -1.65 z-score, lower limit of normal [LLN] and FVC < -1.65 z-score, respectively) and those with FEV1 < -1.65 z-score to those with normal spirometry in adjusted logistic regression analysis. Airway obstruction, pulmonary restriction, and FEV1 < LLN were associated with less time spent in moderate (adjusted odds ratio [OR] 0.63, 95% confidence interval [CI] 0.40-0.99; OR 0.65, 95% CI 0.43-1.00; OR 0.58, 95% CI 0.39-0.87, respectively) and moderate-to-vigorous level of PA (OR 0.65, 95% CI 0.43-0.98; OR 0.63, 95% CI 0.42-0.94; OR 0.56, 95% CI 0.38-0.82, respectively). Those with restrictive spirometry had greater time spent sedentary and a lower daily step count when compared to those with normal spirometry. Respective ORs with 95% CIs were 1.09 (1.01-1.19) and 0.85 (0.75-0.96). Our results show the association between impaired pulmonary function and measured lower level of daily PA. Restriction associated with greater time spent sedentary and a lower daily step count when compared with those with normal spirometry, airway obstruction, and FEV1 < LLN.

Indexed as

ExerciseLungAccelerometryAdultAgedCross-Sectional StudiesFemaleFinlandForced Expiratory VolumeHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveRespiratory Function TestsSedentary BehaviorSpirometryAccelerometerImpaired spirometryPhysical activityPopulation studyPulmonary function

Identifiers

PMID40707715
PMCPMC12289899

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.