Evidence map›Paper›PMID 40707688›Full record

SynthesisSurgery today2026

Jejunal and colonic reconstruction after esophagectomy in difficult gastric conduit: a multicenter study and meta-analysis.

Tomohiko Yasuda, Akihisa Matsuda, Nobutoshi Hagiwara, Keisuke Mishima, Takeshi Matsutani, Satoshi Nomura, Hiroshi Makino, Keisuke Minamimura, Masanori Watanabe, Yoshiharu Nakamura and 1 more

Abstract readMeta-AnalysisMulticenter StudyComparative Study
PubMed Publisher
In one paragraph

Synthesis in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tomohiko YasudaDepartment of Gastroenterological Surgery, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 270-1694, Japan.
Akihisa MatsudaDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan. a-matsu@nms.ac.jp.
Nobutoshi HagiwaraDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Keisuke MishimaDepartment of Gastroenterological Surgery, Nippon Medical School Musashikosugi Hospital, 1-383, Kosugimachi Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan.
Takeshi MatsutaniDepartment of Gastroenterological Surgery, Nippon Medical School Musashikosugi Hospital, 1-383, Kosugimachi Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan.
Satoshi NomuraDepartment of Gastroenterological Surgery, Nippon Medical School Tama Nagayama Hospital, 1-7-1, Nagayama, Tama, Tokyo, 206-8512, Japan.
Hiroshi MakinoDepartment of Gastroenterological Surgery, Nippon Medical School Tama Nagayama Hospital, 1-7-1, Nagayama, Tama, Tokyo, 206-8512, Japan.
Keisuke MinamimuraDepartment of Gastroenterological Surgery, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 270-1694, Japan.
Masanori WatanabeDepartment of Gastroenterological Surgery, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 270-1694, Japan.
Yoshiharu NakamuraDepartment of Gastroenterological Surgery, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 270-1694, Japan.
Hiroshi YoshidaDepartment of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhen using the stomach for esophageal reconstruction is not viable, the jejunum or colon is used, but the optimal choice of organ remains unclear.

methodsWe conducted this multicenter retrospective cohort study to compare the short-term outcomes of patients who underwent jejunal or colonic reconstruction across four centers between January 2011 and March 2023. We also conducted a meta-analysis of studies published before November 2024 using the Mantel-Haenszel random-effects model to compare cervical anastomosis outcomes between jejunal and colonic reconstruction after esophageal cancer surgery.

resultsVascular anastomosis was more frequent in the jejunal group (n = 16; p = 0.001), whereas simultaneous gastrectomy was more common in the colonic group (n = 13; p = 0.029). No significant differences were observed in anastomotic leakage (31.3 vs. 46.2%, p = 0.466), graft necrosis (6.3 vs. 0.0%, p = 1), or hospital mortality (6.3 vs. 7.7%, p = 1) between the groups. The meta-analysis showed a trend toward reduced leakage for jejunal reconstruction with vascular anastomosis (OR = 0.42, 95% CI = 0.16-1.01, p = 0.05). Other outcomes were similar.

conclusionsThe short-term outcomes of jejunal and colonic reconstructions were comparable. Jejunal reconstruction with vascular anastomosis may reduce leakage, but its prognostic benefits remain unclear.

trial registrationno. M-2023-102.

Indexed as

ColonEsophageal NeoplasmsEsophagectomyJejunumPlastic Surgery ProceduresStomachAgedAnastomosis, SurgicalAnastomotic LeakFemaleGastrectomyHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesColonEsophagectomyJejunumPostoperative complicationsReconstruction

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.