Evidence map›Paper›PMID 40707584›Full record

ArticleNPJ digital medicine2025

Artificially intelligent nasal perception for rapid sepsis diagnostics.

Joonchul Shin, Gwang Su Kim, Seongmin Ha, Taehee Yoon, Junwoo Lee, Taehoon Lee, Woong Heo, Kyungyeon Lee, Seong Jun Park, Sunyoung Park and 7 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Joonchul Shin *School of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea.
Gwang Su Kim *Electronic Materials Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
Seongmin Ha *School of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea.
Taehee Yoon *George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Junwoo LeeDepartment of Molecular Science and Technology, Ajou University, Suwon, Republic of Korea.
Taehoon LeeSchool of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea.
Woong HeoSchool of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea.
Kyungyeon LeeSchool of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea.
Seong Jun ParkThe Dabom Inc, Seoul, Republic of Korea.
Sunyoung ParkSchool of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea.
Jaewoo SongDepartment of Laboratory Medicine, College of Medicine, Yonsei University, Seoul, Republic of Korea.
Sunghoon HurElectronic Materials Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
Hyun-Cheol SongMaterials Science and Engineering, Korea University, Seoul, Republic of Korea.
Ji-Soo JangElectronic Materials Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea. wkdwltn92@kist.re.kr.
Jin-Sang KimElectronic Materials Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea. jskim@kist.re.kr.
Hyo-Il JungSchool of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea. uridle7@yonsei.ac.kr.
Chong-Yun KangElectronic Materials Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea. cykang@kist.re.kr.

Funding

Korea Institute of Science and Technology 2E33181, 2V10301, and 2V10120Ministry of Trade, Industry and Energy 00144157National Research Foundation of Korea 2020R1A5A1018052National Research Foundation of Korea 2021R1A6A3A14038599National Research Foundation of Korea RS-2024-00333848National Research Foundation of Korea RS-2024-00356330
6 · The paper itself

Abstract

Sepsis, a life-threatening disease caused by infection, presents a major global health challenge due to its high morbidity and mortality rates. A rapid and precise diagnosis of sepsis is essential for better patient outcomes. However, conventional diagnostic methods, such as bacterial cultures, are time-consuming and can delay sepsis diagnosis. Considering these, researchers investigated alternative techniques that detect volatile organic compounds (VOCs) produced by bacteria. In this study, we designed colorimetric gas sensor arrays, which change color upon interaction with biomarkers, offer a direct visual signal, and demonstrate high sensitivity and specificity in detecting sepsis-related VOCs. Furthermore, an artificial intelligence (AI) based algorithm, Rapid Sepsis Boosting (RSBoost), was employed as an analytical technique to enhance diagnostic accuracy (96.2%) in blood sample. This approach significantly improves the speed and accuracy of sepsis diagnostics within 24 h, holding great potential for transforming clinical diagnostics, saving lives, and reducing healthcare costs.

Identifiers

PMID40707584
PMCPMC12290094

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.