Evidence map›Paper›PMID 40707576›Full record

ArticleNPJ precision oncology2025

Role of large language models in the multidisciplinary decision-making process for patients with renal cell carcinoma: a pilot experience.

Riccardo Bertolo, Lorenzo De Bon, Filippo Caudana, Greta Pettenuzzo, Sarah Malandra, Chiara Casolani, Andrea Zivi, Emanuela Fantinel, Alessandro Borsato, Riccardo Negrelli and 7 more

Abstract read
In one paragraph

Article in NPJ precision oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Riccardo BertoloDepartment of Surgery, Dentistry, Pediatrics and Gynecology, Urology Unit, Azienda Ospedaliera Universitaria Integrata, University of Verona, Verona, Italy. riccardogiuseppe.bertolo@univr.it.
Lorenzo De BonDepartment of Surgery, Dentistry, Pediatrics and Gynecology, Urology Unit, Azienda Ospedaliera Universitaria Integrata, University of Verona, Verona, Italy.
Filippo CaudanaDepartment of Surgery, Dentistry, Pediatrics and Gynecology, Urology Unit, Azienda Ospedaliera Universitaria Integrata, University of Verona, Verona, Italy.
Greta PettenuzzoDepartment of Surgery, Dentistry, Pediatrics and Gynecology, Urology Unit, Azienda Ospedaliera Universitaria Integrata, University of Verona, Verona, Italy.
Sarah MalandraDepartment of Surgery, Dentistry, Pediatrics and Gynecology, Urology Unit, Azienda Ospedaliera Universitaria Integrata, University of Verona, Verona, Italy.
Chiara CasolaniDepartment of Surgery, Dentistry, Pediatrics and Gynecology, Urology Unit, Azienda Ospedaliera Universitaria Integrata, University of Verona, Verona, Italy.
Andrea ZiviDepartment of Medicine, Section of Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Emanuela FantinelDepartment of Medicine, Section of Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Alessandro BorsatoUnit of Radiology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Riccardo NegrelliUnit of Radiology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Emiliano Salah El Din TantawyUnit of Radiation Oncology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
Giulia VolpiUnit of Radiation Oncology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
Matteo BrunelliDepartment of Diagnostic and Public Health, Section of Pathology, University of Verona, Verona, Italy.
Alessandro VecciaDepartment of Surgery, Dentistry, Pediatrics and Gynecology, Urology Unit, Azienda Ospedaliera Universitaria Integrata, University of Verona, Verona, Italy.
Maria Angela CerrutoDepartment of Surgery, Dentistry, Pediatrics and Gynecology, Urology Unit, Azienda Ospedaliera Universitaria Integrata, University of Verona, Verona, Italy.
Alessandro AntonelliDepartment of Surgery, Dentistry, Pediatrics and Gynecology, Urology Unit, Azienda Ospedaliera Universitaria Integrata, University of Verona, Verona, Italy.
AOUI Verona Uro-Oncology Multi-Disciplinary Team

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated an AI chatbot's ability to suggest diagnostic and therapeutic pathways for renal cell carcinoma (RCC) in a multidisciplinary tumor board (MDT). A retrospective analysis of 103 cases (2023-2024) found 62.1% agreement with MDT decisions (κ = 0.44, p< 0.001). Concordance was highest in when follow-up imaging was suggested (p = 0.001), with disease status influencing agreement (p = 0.004). These results suggest AI could assist in RCC case assessments, warranting further research.

Identifiers

PMID40707576
PMCPMC12289931

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.