Evidence map›Paper›PMID 40707575›Full record

ArticleScientific reports2025

The origin of modern North Africans as depicted by a massive survey of mitogenomes.

Giulia Colombo, Elisabetta Moroni, Alessandro Raveane, Nicola Rambaldi Migliore, Vincenzo Agostini, Rosalinda Di Gerlando, Claudio Fiorini, Leonardo Caporali, Francesca Gandini, Elena Raimondi and 13 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Giulia ColomboDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, 27100, Italy.
Elisabetta MoroniDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, 27100, Italy.
Alessandro RaveaneDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, 27100, Italy.
Nicola Rambaldi MiglioreDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, 27100, Italy.
Vincenzo AgostiniDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, 27100, Italy.
Rosalinda Di GerlandoDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, 27100, Italy.
Claudio FioriniIRCCS Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, 40139, Italy.
Leonardo CaporaliIRCCS Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, 40139, Italy.
Francesca GandiniB-Cell Neoplasia Unit and Strategic Research Program on CLL, IRCCS Ospedale San Raffaele, Milan, Italy.
Elena RaimondiDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, 27100, Italy.
Eugenia D'AtanasioIstituto di Biologia e Patologia Molecolari (IBPM), Consiglio Nazionale delle Ricerche (CNR), Rome, 00185, Italy.
Hovirag LancioniDepartment of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, 06123, Italy.
Valerio CarelliIRCCS Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, 40139, Italy.
Maria PalaSchool of Applied Sciences, University of Huddersfield, HD1 3DH, Queensgate, Huddersfield, England, UK.
Beniamino TrombettaDipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza Università di Roma, Rome, 00185, Italy.
Andrea NovellettoDepartment of Biology, University of Rome "Tor Vergata", Rome, 00133, Italy.
Jean-Michel DugoujonLaboratoire d'Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), UMR 5288, Université Paul Sabatier Toulouse III, Toulouse, 31073, France.
Alessandro AchilliDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, 27100, Italy.
Antonio TorroniDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, 27100, Italy.
Martin B RichardsSchool of Applied Sciences, University of Huddersfield, HD1 3DH, Queensgate, Huddersfield, England, UK.
Fulvio CrucianiDipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza Università di Roma, Rome, 00185, Italy.
Ornella SeminoDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, 27100, Italy.
Anna OlivieriDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, 27100, Italy. anna.olivieri@unipv.it.

Funding

Ministero dell'Università e della Ricerca PRIN2022 20224PBY5KMinistero dell'Università e della Ricerca PRIN2022 2022BZYFBEMinistero dell'Università e della Ricerca PRIN2022 2022SNEBJYMinistero dell'Università e della Ricerca PRIN2022 2022Y8BSAL
6 · The paper itself

Abstract

North Africa occupies a unique geographical position in the Mediterranean basin. The genetic profile of modern North African populations is the result of ancient and recent movements of people and periods of isolation. In this paper, we provide a comprehensive mitogenome analysis based on unbiased population sampling from across North Africa including a dataset of 733 modern (238 of which new) and 43 ancient mitogenomes from Morocco, Algeria, Tunisia, Libya and Egypt, compared with modern mitogenomes from Eurasia and sub-Saharan Africa. Our analyses, based on a phylogeographic and demographic approach suggest that mitogenome variability in North African populations (i) can be traced back to three main origins - Eurasia, North Africa and sub-Saharan Africa - and (ii) has been defined during crucial key time periods - from the Palaeolithic to the last millennia. In particular, we identified a signal for population movements from sub-Saharan Africa to North Africa during the favourable climatic period of the Green Sahara, providing evidence from complete mitogenomes that the human dispersals associated with this period also involved females.

Indexed as

DNA, MitochondrialGenome, MitochondrialNorth African PeopleAfrica, NorthernFemaleGenetics, PopulationHuman MigrationHumansPhylogenyPhylogeographyDNA, Mitochondrial

Identifiers

PMID40707575
PMCPMC12289972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.