ArticleNature communications2025
Nanowhisker glues for fatigue-resistant bioadhesion and interfacial functionalization.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Conductive hydrogel bioelectronics for chronic neuromodulation: From biomimetic design and bioactive interfaces to integrated neural platforms.Materials today. Bio · 2026Article
- Bacteria-mimetic bioadhesives with multivalent mucoadhesion and drug-compatible delivery.Materials horizons · 2026Article
- Colloidal Deacetylation of Chitin Nanocrystals Results in Amorphous and Patchy Chitosan Chains.ACS nano · 2026Article
- Anatomy changes, signalling pathways, and clinical treatment after ankle sprain.Bone & joint research · 2026Article
- On-Demand Chemically Degradable Hydrogels for Biological Applications.Chembiochem : a European journal of chemical biology · 2026Review
- Under-Urine-Adhered Supramolecular Hydrogel with Linearly Sustained Quercetin Release Facilitates Hemorrhagic Cystitis Healing via Inflammation Regulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Fatigue-resistant functional bioadhesion is desired in diverse applications ranging from wound management to wearable devices. Nanoparticle-based bioadhesives offer versatile functionality but suffer from weak adhesion and fatigue vulnerability due to tissue barriers and poor tissue interactions. Polymer chain-based bioadhesives can form tough bioadhesion but remain vulnerable to fatigue fracture. Here we demonstrate that rationally designed chitosan nanowhiskers glues achieve fatigue-resistant bioadhesion and interfacial functionalization via the combined high aspect ratio, rigidity, polymer-binding and network-forming properties. We deploy these glues using chemical enhancers, microneedle rollers, and ultrasound, enabling strong tissue anchorage despite tissue barriers. At low concentrations, the nanowhisker glue paired with a tough hydrogel achieves an interfacial fatigue threshold of 382 J m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.