Evidence map›Paper›PMID 40707419›Full record

Trial reportObesity (Silver Spring, Md.)2025

An eHealth Intervention in Pregnancy on Maternal Body Composition and Subsequent Perinatal Outcomes: A Randomized Trial.

Maryam Kebbe, Kaja Falkenhain, Robbie Beyl, Abby D Altazan, Emily W Flanagan, Chelsea L Kracht, Hannah E Cabre, Emily K Woolf, Daniel S Hsia, John W Apolzan and 1 more

Registry-linked trialAbstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04028843 (SmartMoms in WIC), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04028843 nacompletednot on this map

SmartMoms in WIC: A Smartphone Intervention for WIC Mothers to Improve Nutrition and Weight Gain During Pregnancy

TypeinterventionalSponsorPennington Biomedical Research CenterRan2019 to 2025Enrolled351ConditionsWeight Gain During PregnancyArmsHealthy Beginnings
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maryam KebbePennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Kaja FalkenhainPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.ORCID https://orcid.org/0000-0002-3240-964X
Robbie BeylPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Abby D AltazanPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Emily W FlanaganPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Chelsea L KrachtPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Hannah E CabrePennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Emily K WoolfPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.ORCID https://orcid.org/0009-0007-1546-865X
Daniel S HsiaPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
John W ApolzanPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.ORCID https://orcid.org/0000-0001-8492-7820
Leanne M RedmanPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.ORCID https://orcid.org/0000-0002-7267-7374

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI ROBERT A KESTERSON · 2005 to 2026
$26.5M
longitudinal assessment of stress and stress-related concepts across a behavioral weight loss interventionP20GM144269 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI STEVEN A WEINMAN · 2022 to 2026
$14.9M
Training in Obesity ResearchT32DK064584 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI CORBY K MARTIN, Christopher D Morrison · 2003 to 2026
$5.3M
A pragmatic, scalable e-health intervention for management of gestational weight gain in low-income mothersR01NR017644 · NINR · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI REDMAN, LEANNE MAREE · 2019 to 2024
$3.6M
Promoting fat loss during pregnancy in women with grade 2 and 3 obesityR01DK124806 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI PHELAN, SUZANNE, REDMAN, LEANNE MAREE · 2020 to 2024
$3.2M
Determinants of gestational weight gain in obese pregnant womenR01DK099175 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI REDMAN, LEANNE MAREE · 2013 to 2015
$1.8M
An Examination of Brown Adipose Tissue and Energy Expenditure in InfantsF32HD108022 · NICHD · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI FLANAGAN, EMILY W · 2022 to 2024
$229k
A home-based intervention to improve adherence to the 24-Hour Movement Guidelines in young childrenK99HD107158 · NICHD · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI KRACHT, CHELSEA L · 2022 to 2023
$213k
Examining dietary and metabolomics patterns on cardiometabolic outcome variability in response to calorie restrictionF32HL176217 · NHLBI · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI WOOLF, EMILY KATLYN · 2024 to 2025
$158k
Louisiana Clinical and Translational Sciences Center U54GM104940NHLBI NIH HHS F32 HL176217NICHD NIH HHS F32 HD108022NICHD NIH HHS K99 HD107158NICHD NIH HHS L40 HD109931NIDDK NIH HHS P30 DK072476NIDDK NIH HHS R01 DK099175NIDDK NIH HHS R01 DK124806NIDDK NIH HHS T32 DK064584NIGMS NIH HHS P20 GM144269NIGMS NIH HHS U54 GM104940NINR NIH HHS 5R01NR017644NINR NIH HHS F32HD108022NINR NIH HHS F32HL176217NINR NIH HHS K99HD107158NINR NIH HHS P20GM144269NINR NIH HHS R01 NR017644NINR NIH HHS T32DK064584Pennington/Louisiana Nutrition and Obesity Research Center P30DK072476
6 · The paper itself

Abstract

objectiveTo examine the effects of a pragmatic multicomponent eHealth intervention in pregnancy on body composition changes and subsequent associations with perinatal outcomes.

methodsPregnant individuals (n = 351) enrolled in Louisiana's Women, Infants, and Children program were randomly assigned to a multicomponent eHealth Intervention or Usual Care. Fat percentage, fat mass, and fat-free mass were assessed using bioelectrical impedance at trimester-specific study visits. Mixed models evaluated within- and between-group differences in body composition from early to late pregnancy: overall, by BMI, and by gestational weight gain (GWG) guideline attainment. Effects of body composition changes on perinatal outcomes was evaluated.

resultsCompared to Usual Care (n = 172), the Intervention Group (n = 179) had attenuated gains in fat mass, fat mass index, and fat percentage from early to late pregnancy overall, in individuals who had normal weight at enrollment, and in those who exceeded GWG guidelines (p < 0.05). No significant between-group differences in fat-free mass were observed. Fat mass change interacted with intervention effects on neonatal health outcomes (p = 0.01).

conclusionsLifestyle interventions during pregnancy may attenuate gestational fat mass gain, particularly among women with normal weight and those who exceed GWG guidelines, with potential implications for neonatal health outcomes.

trial registrationClinicalTrials.gov identifier: NCT04028843.

Indexed as

Body CompositionAdultBody Mass IndexFemaleGestational Weight GainHumansInfant, NewbornLouisianaPregnancyPregnancy ComplicationsPregnancy OutcomePrenatal CareTelemedicineYoung Adultbody compositiongestational weight gainneonateobesitypregnancy

Identifiers

PMID40707419
PMCPMC12440120

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.