ArticleInternal medicine (Tokyo, Japan)2026
Development of Nephritis and Abnormal Lung Shadow in a Patient with IgG4-related Hypertrophic Pachymeningitis with MPO-ANCA Positivity after Unplanned Interruption of Maintenance Glucocorticoid Therapy.
Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
We herein report a patient with immunoglobulin (Ig) G4-related hypertrophic pachymeningitis (HP) with myeloperoxidase (MPO)-antineutrophil cytoplasmic antibody (ANCA) positivity without renal dysfunction at the time of the diagnosis who subsequently developed nephritis after an unplanned interruption of maintenance glucocorticoid therapy. A renal biopsy specimen obtained at the time of the development of renal dysfunction revealed the possibility of both ANCA-associated nephritis and IgG4-related tubulointerstitial nephritis, with no HP relapse. The present case highlights the need to monitor other organ complications, including renal damage, in patients with IgG4-related HP with MPO-ANCA positivity, even after achieving remission.
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