Evidence map›Paper›PMID 40707218›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Diffuse Alveolar Hemorrhage Caused by Metastatic Breast Cancer.

Masayoshi Higashiguchi, Setsuko Yoshioka, Taishiro Mizukoshi, Reiko Inada, Fukuko Okabe, Satoshi Tetsumoto

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masayoshi HigashiguchiDepartment of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Japan.
Setsuko YoshiokaDepartment of Surgery, Suita Municipal Hospital, Japan.
Taishiro MizukoshiDepartment of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Japan.
Reiko InadaDepartment of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Japan.
Fukuko OkabeDepartment of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Japan.
Satoshi TetsumotoDepartment of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 68-year-old woman presented with a history of hemoptysis. She had been receiving hormone therapy and chemotherapy for recurrent breast cancer. She was diagnosed with diffuse alveolar hemorrhage caused by metastatic breast cancer, as evidenced by increasingly bloody bronchoalveolar lavage fluid and malignant cells in multiple lung lobes. This condition was associated with tumor emboli in the pulmonary vasculature and transformation into a hormone receptor-negative state. Serial changes in chest computed tomography findings, from diffuse patchy ground-glass opacities to multiple nodules, are notable. This rare mode of metastasis may be associated with a poor prognosis.

Indexed as

Breast NeoplasmsHemorrhageLung NeoplasmsPulmonary AlveoliAgedFemaleHemoptysisHumansTomography, X-Ray Computedbreast cancerbronchoscopydiffuse alveolar hemorrhage

Identifiers

PMID40707218
PMCPMC12979747

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.