ArticleEuropean endodontic journal2025
Antimicrobial Effectiveness of High-Power Sonic and Ultrasonic Devices Combined with Stepwise Intraoperative or Final Activation of Sodium Hypochlorite.
Article in European endodontic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Comparison of Laser and Conventional Root Canal Disinfection Protocols in an dual-biofilm in-vitro model.Lasers in medical science · 2026Article
- Influence of repeated cycles of full-strength sodium hypochlorite activation on the mechanical behavior of root canal-treated teeth: a laboratory study.BMC oral health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study investigated the intratubular decontamination promoted by high-power sonic and ultrasonic devices using either a stepwise intraoperative activation (SIA) technique or a final conventional activation (CA) approach during root canal chemomechanical preparation.
methodsFifty human lower premolars were contaminated with Enterococcus faecalis and assigned into five groups (n=8): conventional syringe irrigation (CSI); final ultrasonic activation (FUA) using the ultrasonic insert 25/25 IRRI S; final sonic agitation (FSA) using the high-power sonic insert 20/28 Eddy system (both CA techniques); stepwise ultrasonic activation (SUA); and stepwise sonic agitation (SSA) using the same devices during and after canal preparation (SIA techniques). Remaining specimens served as controls. Root canal preparation was performed with the Reciproc system and 5.25% NaOCl, followed by final irrigation with 17% EDTA. Bacterial viability was assessed via confocal microscopy with Live/Dead technique. Statistical analysis was employed using non-parametric tests (α=0.05).
resultsSUA showed the lowest bacterial viability, followed by FSA, both statistically similar. SSA and FUA were similar but less effective than SUA and FSA (p<0.05). The CSI group had significantly higher bacterial viability compared to all other groups (p<0.05).
conclusionHigh-power sonic agitation and ultrasonic activation enhanced intratubular decontamination against E. faecalis. The SIA technique, using IRRI S or Eddy systems, effectively reduced bacterial viability and represents a promising approach for root canal disinfection. (EEJ-2024-11-185).
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