Evidence map›Paper›PMID 40705397›Full record

ArticleEmerging infectious diseases2025

ACE2 Receptor Usage across Animal Species by SARS-CoV-2 Variants.

Masato Hatta, Gloria P Larson, Yasuko Hatta, Wei Wang, Nannan Jiang, Yu-Jin Jung, Li Wang, Xiaoyu Fan, Brenda M Calderon, Gaston Bonenfant and 8 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Masato Hatta
Gloria P Larson
Yasuko Hatta
Wei Wang
Nannan Jiang
Yu-Jin Jung
Li Wang
Xiaoyu Fan
Brenda M Calderon
Gaston Bonenfant
Xudong Lin
Chenchen Feng
Dan Cui
Ginger Atteberry
Michael Currier
John Steel
David E Wentworth
Bin Zhou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We analyzed the receptor-binding activity and infectivity of 6 representative SARS-CoV-2 lineages in cell lines expressing angiotensin-converting enzyme 2 proteins from 54 different animal species. All viruses demonstrated infectivity in a broad range of species. Susceptible animal species could serve as natural reservoirs or intermediate hosts for SARS-CoV-2.

Indexed as

Angiotensin-Converting Enzyme 2COVID-19Receptors, VirusSARS-CoV-2AnimalsCell LineHumansSpecies SpecificitySpike Glycoprotein, CoronavirusACE2 protein, humanAngiotensin-Converting Enzyme 2Receptors, VirusSpike Glycoprotein, CoronavirusACE2coronavirus diseaseCOVID-19One Healthrespiratory infectionsSARS-CoV-2severe acute respiratory syndrome coronavirus 2viruseszoonoses

Identifiers

PMID40705397
PMCPMC12309770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.