Evidence map›Paper›PMID 40705137›Full record

Observational studyLung2025

Airway Mucus Plugs in Patients with Chronic Cough: A Single-Center Observational Study.

Kyongmin Sarah Beck, Dae Hee Han, Hyun-Seob Jeon, Juyoung Shin, Sook Young Lee, Woo-Jung Song, Hwa Young Lee

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Lung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kyongmin Sarah Beck *Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Dae Hee Han *Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Hyun-Seob JeonDivision of Allergy, Department of Internal Medicine, St Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Republic of Korea.
Juyoung ShinHealth Promotion Center, Seoul St. Mary's Hospital, Seoul, Republic of Korea.
Sook Young LeeDivision of Allergy, Department of Internal Medicine, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-Daero, Seocho-Gu, Seoul, 06591, Korea.
Woo-Jung SongDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Hwa Young LeeDivision of Allergy, Department of Internal Medicine, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-Daero, Seocho-Gu, Seoul, 06591, Korea. lehwyo@catholic.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study investigated the prevalence of mucus plugs and their clinical associations in patients with chronic cough.

methodsChest computed tomography (CT) scans were evaluated in patients with chronic cough and healthy controls.

resultsAmong 82 patients with chronic cough and 71 controls, mucus plugs were identified in 31.7% and 5.6%, respectively. Higher mucus plug scores were associated with older age, elevated fractional exhaled nitric oxide (FeNO), and lower total Cough Hypersensitivity Questionnaire (CHQ) scores (all P < 0.05). Regression analysis revealed associations with higher FeNO and lower total CHQ scores (Model 1: R

conclusionsMucus plugs were prevalent in chronic cough and associated with type 2 airway inflammation. Their clinical significance warrants further investigation.

Indexed as

CoughMucusAdultAgedAge FactorsBreath TestsCase-Control StudiesChronic CoughChronic DiseaseFemaleHumansImmunoglobulin EMaleMiddle AgedNitric OxidePrevalenceImmunoglobulin ENitric OxideChronic coughMucusTomography

Identifiers

PMID40705137

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.