Evidence map›Paper›PMID 40705112›Full record

SynthesisPediatric surgery international2025

Postoperative outcomes of robotic-assisted vs. laparoscopic pull-through surgery in pediatric Hirschsprung's disease: a systematic review and meta-analysis.

Carla Isabella Miret Durazo, Paloma Frei, Stephanie Gail Giray Go, Rafeeqa Binte Ameenuthin, M J Marie Caragon Baptista, Francesca Gabriela Ocana Diaz, Yadelys Rodriguez Reyes, Sylvia Oluwafunmilayo Ejinaka, Abdulrahman Abdulkarim Shawish, Evelyn Saavedra Reyna and 3 more

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carla Isabella Miret DurazoUniversity of California, Irvine, Orange, CA, USA. miret.isa@gmail.com.
Paloma FreiUniversidad Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Stephanie Gail Giray GoOur Lady of Fatima University - College of Medicine, Valenzuela, Philippines.
Rafeeqa Binte AmeenuthinZhejiang University School of Medicine, Hangzhou, China.
M J Marie Caragon BaptistaOur Lady of Fatima University - College of Medicine, Valenzuela, Philippines.
Francesca Gabriela Ocana DiazUniversidad Peruana de Ciencias Aplicadas, Escuela de Medicina, Lima, Peru.
Yadelys Rodriguez ReyesUniversidad de Oriente, Núcleo Anzoatégui, Barcelona, Venezuela.
Sylvia Oluwafunmilayo EjinakaShenyang Medical College, Shenyang, Liaoning Province, China.
Abdulrahman Abdulkarim ShawishIlia State University - Faculty of Medicine, Tbilisi, Georgia.
Evelyn Saavedra ReynaUniversidad Autónoma de Nuevo León, Monterrey, Mexico.
Saimuralidhar S SrinivasanSri Ramachandra Institute of Higher Education and Research, Chennai, India.
Stephani Carolina Salvatierra MorenoUniversidad de los Andes Mérida, Mérida, Venezuela.
Victor Sebastan ArruaranaBrookdale University Hospital and Medical Center, Brooklyn, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hirschsprung's disease (HSCR) is a congenital bowel disorder caused by absent enteric ganglion cells, often in neonates with intestinal obstruction. Minimally invasive surgical resection is the standard treatment. Robotic-assisted pull-through surgery (RAS) offers improved precision, but comparative data with laparoscopic-assisted surgery (LAS) is limited. This systematic review and meta-analysis evaluated postoperative outcomes between RAS and LAS in pediatric HSCR. Literature search was performed in PubMed/MEDLINE, Web of Science, Scopus, EMBASE, CINAHL, and Cochrane Library, following PRISMA guidelines. Random-effects meta-analysis with 95% confidence interval (CI) was conducted. Protocol was preregistered on PROSPERO (CRD420251033648). Four studies involving 291 pediatric patients (124 RAS, 167 LAS) were included. RAS demonstrated significantly lower blood loss (MD = - 2.66; 95% CI - 4.54 to - 0.80; p < 0.01) and higher hospitalization expenses (MD = 44,922.20; 95% CI 43,592.28-46,252.12; p < 0.01). LAS presented shorter postoperative feed times (MD = 1.00; 95% CI 0.16-1.84; p = 0.02). No significant differences were observed in other postoperative outcomes. RAS appears to be a safe alternative to LAS in pediatric HSCR. However, no definitive clinical advantage of RAS is confirmed. Further studies are warranted to clarify its role in pediatric colorectal surgery.

Indexed as

Hirschsprung DiseaseLaparoscopyRobotic Surgical ProceduresChildHumansPostoperative ComplicationsTreatment OutcomeHirschsprung’s associated enterocolitisHirschsprung’s diseaseLaparoscopic-assisted surgeryRobotic-assisted surgery

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.