ArticleExperimental & applied acarology2025
Functional analysis of Mu-class glutathione S-transferase HdGSTm1 from Haemaphysalis doenitzi with a focus on the roles in the tick blood sucking.
Article in Experimental & applied acarology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- RNAi-based functional analysis of a theta-class glutathione S-transferase implicated in deltamethrin detoxification inFrontiers in physiology · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
During blood feeding, ticks face significant oxidative stress due to hemoglobin breakdown. In this context, GSTs are proposed to act as critical antioxidants, possibly by detoxifying lipid peroxides. The transcriptome of H. doenitzi was screened for GST genes, followed by the recombinant expression and functional analysis of these genes. Specifically, HdGSTm1 was cloned by PCR, and the recombinant protein rHdGSTm1 was expressed and purified. The properties of rHdGSTm1 were analyzed, gene transcription was assessed, and RNA interference was employed to evaluate its functional impact. As results, the open reading frame of HdGSTm1 is 693 base pairs (bp) in length and number of coding amino acids is 230 and it belongs to Mu-class GSTs. And the activity of GST for GSH was measured (V
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