Evidence map›Paper›PMID 40705004›Full record

ArticleeLife2025

Meioc-Piwil1 complexes regulate rRNA transcription for differentiation of spermatogonial stem cells.

Toshihiro Kawasaki, Toshiya Nishimura, Naoki Tani, Carina Ramos, Emil Karaulanov, Minori Shinya, Kenji Saito, Emily Taylor, René F Ketting, Kei-Ichiro Ishiguro and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Toshihiro KawasakiDepartment of Gene Function and Phenomics, National Institute of Genetics, Mishima, Japan.
Toshiya NishimuraGraduate School of Science, Nagoya University, Nagoya, Japan.
Naoki TaniInstitute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan.
Carina RamosBiology Department, University of Massachusetts Boston, Boston, United States.
Emil KaraulanovInstitute of Molecular Biology (IMB), Mainz, Germany.
Minori ShinyaDepartment of Gene Function and Phenomics, National Institute of Genetics, Mishima, Japan.
Kenji SaitoDepartment of Gene Function and Phenomics, National Institute of Genetics, Mishima, Japan.
Emily TaylorBiology Department, University of Massachusetts Boston, Boston, United States.
René F KettingInstitute of Molecular Biology (IMB), Mainz, Germany.ORCID https://orcid.org/0000-0001-6161-5621
Kei-Ichiro IshiguroInstitute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan.ORCID https://orcid.org/0000-0002-7515-1511
Minoru TanakaGraduate School of Science, Nagoya University, Nagoya, Japan.
Kellee R SiegfriedBiology Department, University of Massachusetts Boston, Boston, United States.ORCID https://orcid.org/0000-0002-7951-392X
Noriyoshi SakaiDepartment of Gene Function and Phenomics, National Institute of Genetics, Mishima, Japan.ORCID https://orcid.org/0000-0001-8403-8281

Funding

Initiative for Maximizing Student Diversity at UMass BostonR25GM076321 · NIGMS · UNIVERSITY OF MASSACHUSETTS BOSTON · PI COLON-CARMONA, ADAN, SKVIRSKY, RACHEL · 2008 to 2022
$4.5M
Spermatogonial stem cell regulation and maintenance of male fertilityR15HD107594 · NICHD · UNIVERSITY OF MASSACHUSETTS BOSTON · PI SIEGFRIED, KELLEE R · 2022 to 2022
$458k
Japan Science and Technology Agency Jst-A step JPMJTR204FJapan Society for the Promotion of Science JP23116709Japan Society for the Promotion of Science JP25114003Japan Society for the Promotion of Science JP25251034Kumamoto University Inter-University Research Network for High Depth Omics, IMEG, Kumamoto UniversityNICHD NIH HHS R15 HD107594NIGMS NIH HHS R25 GM076321NIH HHS The UMB Initiative for Maximizing Student Development program, NIH award R25 GM076321
6 · The paper itself

Abstract

Ribosome biogenesis is vital for sustaining stem cell properties, yet its regulatory mechanisms are obscure. Herein, we show unique properties of zebrafish

Indexed as

Adult Germline Stem CellsArgonaute ProteinsCell DifferentiationRNA, RibosomalSpermatogoniaTranscription, GeneticZebrafish ProteinsAnimalsMaleZebrafishArgonaute ProteinsRNA, RibosomalZebrafish Proteinsdevelopmental biologymeiocpiwil1rRNA transcriptionspermatogonial stem cellzebrafish

Identifiers

PMID40705004
PMCPMC12289311

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.