Evidence map›Paper›PMID 40704892›Full record

ArticleJournal of virology2025

High genomic stability of Andes virus following successive passage

Bryce M Warner, Jérémie Prévost, Nikesh Tailor, Yvon Deschambault, Angela Sloan, Julina Allarie, Levi Klassen, Kathy Frost, Stephanie Booth, Jonathan Audet and 2 more

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Why Andes hantavirus is not the next SARS-CoV-2: contrasting viral shedding, transmissibility and genomic patterns.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bryce M WarnerVaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, Canada.ORCID 0000-0003-2635-5072
Jérémie PrévostSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Nikesh TailorSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Yvon DeschambaultSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Angela SloanSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Julina AllarieSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Levi KlassenSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Kathy FrostMycobacteriology, Vector-Borne and Prion Diseases Division, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Stephanie BoothDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada.
Jonathan AudetSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.ORCID 0000-0002-0743-7489
Geoff SouleSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
David SafronetzSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.ORCID 0000-0002-9024-728X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Andes virus (ANDV) is a South American hantavirus that causes hantavirus cardiopulmonary syndrome (HCPS), a severe respiratory infection with a case fatality rate as high as 40%. A critical model for studying HCPS is the Syrian hamster model, which faithfully recapitulates key aspects of the disease. Recent studies have shown that strains of ANDV from different origins, i.e., from rodent or human hosts, can produce widely different outcomes in the hamster model. CHI-7913, a human isolate, does not cause lethal disease and replicates poorly in hamster tissues compared with the classical rodent isolate Chile-9717869. Here, we passaged CHI-7913

Indexed as

Genome, ViralGenomic InstabilityHantavirus InfectionsOrthohantavirusAnimalsCricetinaeDisease Models, AnimalHumansMesocricetusMutationSerial PassageVero CellsVirus ReplicationAndes virusdisease modelinghantavirushantavirus pulmonary syndromeorthohantaviruspathogenesisvirulence

Identifiers

PMID40704892
PMCPMC12363185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.