ArticleActa paediatrica (Oslo, Norway : 1992)2025
Maternal Oncological Disease and Congenital Pneumonia Are New Independent Risk Factors for Surfactant Requirements in Late Preterm Infants.
Article in Acta paediatrica (Oslo, Norway : 1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Short-term outcomes associated with surfactant use in respiratory distress in late preterm to early term infants.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
aimThe purpose of this study was to evaluate the incidence of respiratory distress syndrome (RDS) in late preterm (LPT) infants. We also aimed to identify the risk factors associated with surfactant requirement and the clinical outcomes associated with surfactant therapy.
methodsWe retrospectively analysed data from a single-centre neonatology unit at the Fondazione Policlinico Universitario Agostino Gemelli, IRCCS in Rome, Italy over a 4 year period. For each risk factor, the odds ratio (OR) and the 95% confidence interval (95% CI) were reported.
resultsThe incidence of RDS among 1335 LPT infants was 7.8%. The percentage of infants who required the surfactant was 3.4%. Gestational age (OR 0.541, 95% CI 0.367-0.796, p = 0.002), birth weight (OR 1.001, 95% CI 1.000-1.003; p = 0.037), 1 min Apgar score (OR 0.631, 95% CI 0.440-0.905, p = 0.012) and congenital pneumonia (OR 28.931, 95% CI 9.139-91.597, p < 0.001) were the neonatal risk factors associated with surfactant requirement. Oncological disease (OR 4.116, 95% CI 1.081-15.672, p = 0.038) was the maternal risk factor associated with surfactant requirement.
conclusionsMaternal oncological disease and congenital pneumonia emerged as new risk factors for surfactant requirement in LPT infants. These findings expanded the understanding of the mechanisms underlying RDS in LPT infants, moving beyond the known risk factors.
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