ArticleACS applied bio materials2025
Preparation of Organic-Inorganic Hybrid (Sr, Ca)CO
Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Recent advances in bone regeneration materials have focused on the development of artificial bone scaffolds incorporating bioactive ions, such as strontium ions, that promote bone formation. Incorporating drug retention and release capabilities into these materials is expected to not only improve bone regeneration efficiency but also provide additional drug-derived benefits. The aim of this study is to synthesize organic-inorganic hybrid capsules with a shell containing strontium salts that can retain and release therapeutic agents. The synthesized temperature-responsive polymer formed coacervate droplets that could encapsulate hydrophobic model drugs at temperatures above the lower critical solution concentration (LCST). After preparing Pickering emulsions by mixing calcium carbonate powder and coacervate droplets in an aqueous solution, the calcium carbonate on the surface was allowed to grow crystals under various solvent conditions to produce (Ca,Sr)CO
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