Evidence map›Paper›PMID 40704776›Full record

ArticleJournal of neuroscience research2025

Metabolic and Structural Alterations in the Motor System Following Spinal Cord Injury: An In-Vivo

Simon Schading-Sassenhausen, Anna Lebret, Kadir Şimşek, Pauline Gut, Sabrina Imhof, Björn Zörner, Roland Kreis, Patrick Freund, Maryam Seif

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroscience research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Simon Schading-SassenhausenSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-3969-193X
Anna LebretSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0009-0004-1908-4328
Kadir ŞimşekCardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0003-4044-7395
Pauline GutDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0003-0554-4974
Sabrina ImhofSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-4240-9344
Björn ZörnerSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-2246-3359
Roland KreisMagnetic Resonance Methodology, Institute of Diagnostic and Interventional Neuroradiology, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-8618-6875
Patrick FreundSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-4851-2246
Maryam SeifSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-9253-5680

Funding

International Foundation for Research in ParaplegiaSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungWilhelm Hurka FoundationWings for Life
6 · The paper itself

Abstract

Spinal cord injury (SCI) disrupts spinal tracts and neuronal pathways, including those in the primary motor cortex (M1) and the lumbar cord enlargement (LCE) involved in motor control. This study sought to determine whether metabolite concentrations deviate between SCI and healthy controls (HC) in M1 and LCE using proton magnetic resonance spectroscopy (

Indexed as

Motor CortexSpinal CordSpinal Cord InjuriesAdultAgedAspartic AcidAtrophyCreatineFemaleGray MatterHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMiddle AgedProton Magnetic Resonance SpectroscopyAspartic AcidCreatineN-acetylaspartate1H‐MR spectroscopylumbar cordmotor dysfunctionspinal cord injury

Identifiers

PMID40704776
PMCPMC12288631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.