Evidence map›Paper›PMID 40704716›Full record

ArticleThe oncologist2025

Association of social vulnerability index and chimeric antigen receptor T-cell therapy administration, 2018-2023.

Alireza Boloori, Emisa Nategh, Christopher T Su

Abstract read
In one paragraph

Article in The oncologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alireza BolooriMilgard School of Business, University of Washington Tacoma, Tacoma, WA 98402, United States.
Emisa NateghMcDonough School of Business, Georgetown University, Washington, DC 20057, United States.ORCID 0000-0001-6907-9982
Christopher T SuDivision of Hematology and Oncology, University of Washington, Seattle, WA 98195, United States.ORCID 0000-0002-2700-2650

Funding

American Society of Clinical OncologyAmerican Society of Hematology
6 · The paper itself

Abstract

Chimeric antigen receptor T-cell (CAR T) therapy for patients with relapsed/refractory hematologic malignancies demands numerous visits, which may pose challenges for patients with lower socioeconomic status (SES). The Centers for Disease Control and Prevention publishes the Social Vulnerability Index (SVI), which summarizes area-level SES factors that predict how residents respond to stressors, including a new cancer -diagnosis. We used the nationwide MarketScan commercial and Medicare insurance claims database to analyze the association between SVI and CAR T therapy completion. We performed multivariable logistic regressions (adjusting for patient-level covariates) and found that patients with hematologic malignancies residing in areas of higher SVI (lower SES) have decreased odds of CAR T therapy completion (odds ratio [OR] 0.84 for leukemia, P = .02; OR 0.72 for lymphoma, P < .001; OR 0.70 for myeloma, P < .001). Therefore, strategies to mitigate CAR T disparities may be focused on patients living in areas with higher SVI.

Indexed as

Hematologic NeoplasmsImmunotherapy, AdoptiveReceptors, Chimeric AntigenVulnerable PopulationsAgedFemaleHumansMaleMiddle AgedSocial ClassUnited StatesReceptors, Chimeric Antigencell- and tissue-based therapychimeric antigen receptorhealth services accessibilitysocial vulnerability

Identifiers

PMID40704716
PMCPMC12422313

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.