Evidence map›Paper›PMID 40704672›Full record

ReviewInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2025

Cancer in pregnancy: FIGO Best practice advice and narrative review.

Surabhi Nanda, Melanie Nana, Long Nguyen-Hoang, Sumaiya Adam, Fionnuala McAuliffe, Lina Bergman, Sarikapan Wilailak, Orla McNally, Cynthia V Maxwell, Nikhil Purandare and 18 more

Abstract readReview
In one paragraph

Review in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cancer and fertility management: FIGO best practice advice.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Guideline
  2. Article
  3. Article
  4. Cancer diagnosed during pregnancy: a qualitative study of women's psychosocial experiences during treatment and survivorship.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Review
  6. Gastrointestinal cancers in women: The role of sex hormones.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
  7. Article
  8. Cancer in pregnancy: FIGO Best practice advice and narrative review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Surabhi NandaWomen's Directorate, Guy's and St. Thomas' Hospital, Evelina London Children's Hospital, King's College London, London, UK.ORCID https://orcid.org/0000-0003-3955-1304
Melanie NanaWomen's Directorate, Guy's and St. Thomas' Hospital, Evelina London Children's Hospital, King's College London, London, UK.ORCID https://orcid.org/0000-0002-7908-8986
Long Nguyen-HoangDepartment of Obstetrics and Gynecology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Sumaiya AdamDepartment of Obstetrics and Gynecology, School of Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.ORCID https://orcid.org/0000-0001-8769-3273
Fionnuala McAuliffeUCD Perinatal Research Centre, School of Medicine, University College Dublin, National Maternity Hospital, Dublin, Ireland.ORCID https://orcid.org/0000-0002-3477-6494
Lina BergmanDepartment of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Sarikapan WilailakFaculty of Medicine Ramathibodi Hospital, Department of Obstetrics and Gynecology, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0001-7288-494X
Orla McNallyOncology and Dysplasia Services, Royal Women's Hospital, Melbourne, Australia.ORCID https://orcid.org/0000-0001-7340-9489
Cynthia V MaxwellMaternal Fetal Medicine, Sinai Health and Women's College Hospital, University of Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-4734-1251
Nikhil PurandareUniversity of Galway, Galway, Ireland.ORCID https://orcid.org/0000-0002-4718-6979
Bo JacobssonDepartment of Obstetrics and Gynecology, Sahlgrenska University Hospital, Ostra, Gothenburg, Sweden.ORCID https://orcid.org/0000-0001-5079-2374
Virna P MedinaDepartment of Obstetrics and Gynecology, Faculty of Health, Universidad del Valle, Clínica Imbanaco Quirón Salud, Universidad, Libre, Cali, Colombia.ORCID https://orcid.org/0000-0002-0545-2626
Anil KapurWorld Diabetes Foundation, Bagsvaerd, Denmark.
Titus BeyuoDepartment of Obstetrics and Gynecology, University of Ghana Medical School, Accra, Ghana.
Francisco RuilobaFetal Medicine Research Institute, King's College Hospital, London, UK.
Ernesto CastelazoInternational Federation of Gynecology and Obstetrics, London, UK.
Graeme N SmithDepartment of Obstetrics & Gynecology, Kingston Health Sciences Centre, Queen's University, Kingston, Ontario, Canada.
Sharleen L O'ReillyUCD Perinatal Research Centre, School of Medicine, University College Dublin, National Maternity Hospital, Dublin, Ireland.
Patrick O'BrienInstitute for Women's Health, University College London, London, UK.
Mark HansonInstitute of Developmental Sciences, University Hospital Southampton, Southampton, UK.
Mary L RosserDepartment of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York-Presbyterian, New York, New York, USA.
Claudio SosaDepartment of Obstetrics and Gynecology, School of Medicine, University of Uruguay, Montevideo, Uruguay.
Valerie GuintoDepartment of Obstetrics and Gynecology, St. Luke's Medical Center Global City, University of the Philippines-Philippine General Hospital, Manila, Philippines.ORCID https://orcid.org/0000-0003-3108-6727
Jonathan BerekStanford Women's Cancer Center, Laurie Kraus Lacob Professor Stanford University School of Medicine, Stanford, California, USA.
Catherine Nelson-PiercyWomen's Directorate, Guy's and St. Thomas' Hospital, Evelina London Children's Hospital, King's College London, London, UK.ORCID https://orcid.org/0000-0001-9311-1196
Frédéric AmantDivision Gynecologic Oncology, UZ Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-5452-4905
Liona PoonDepartment of Obstetrics and Gynecology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, SAR, China.ORCID https://orcid.org/0000-0002-3944-4130
FIGO Committee on the Impact of Pregnancy on Long‐term Health, FIGO Committee on Women's Cancer, and the FIGO Division of Maternal and Newborn Health

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer during pregnancy is relatively rare. The incidence is underestimated due to the lack of international registries covering both high-income and low- and middle-income countries, and is expected to rise with increasing maternal age and increasing global adoption of cell-free DNA testing for aneuploidy. Physiological changes during pregnancy often make the diagnosis challenging and delayed. Lack of experience and knowledge about this condition may also contribute to late diagnosis, suboptimal management, and occasionally inadvertent fetal and/or maternal harm. The principles of cancer management in pregnancy for most cancer types do not differ significantly from the non-pregnant population. The impact of investigations for diagnosis and staging, risks of surgery, systemic chemotherapy, and/or radiotherapy on fetal well-being and preterm birth need to be considered for treatment and management planning, in addition to maternal wishes. Working in a multidisciplinary setting, ideally with medical and radiation oncologists, surgeons, radiologists, cancer specialist nurses, geneticists, psychologists, teratologists, and clinical pharmacologists, obstetricians, obstetric physicians, neonatologists, and experienced nursing and midwifery staff helps provide optimal care for the woman. This best practice advice aims to provide recommendations on the diagnosis and management of cancer in pregnancy, which can be adopted in all resource settings.

Indexed as

Pregnancy Complications, NeoplasticFemaleHumansPregnancyabortioncancerchemotherapymiscarriagepregnancyprematurityradiotherapystagingtermination

Identifiers

PMID40704672
PMCPMC12447680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.