Evidence map›Paper›PMID 40704663›Full record

ArticleJournal of the science of food and agriculture2025

Kinetic and thermodynamic evaluation of antioxidant reactions: factors influencing the radical scavenging properties of phenolic compounds in foods.

Moeka Yamauchi, Yukino Kitamura, Chihiro Tada, Riku Kato, Hiroaki Gotoh

Abstract read
In one paragraph

Article in Journal of the science of food and agriculture, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Moeka YamauchiDepartment of Applied Chemistry, Yokohama National University, Yokohama, Japan.
Yukino KitamuraDepartment of Applied Chemistry, Yokohama National University, Yokohama, Japan.
Chihiro TadaDepartment of Applied Chemistry, Yokohama National University, Yokohama, Japan.
Riku KatoDepartment of Applied Chemistry, Yokohama National University, Yokohama, Japan.
Hiroaki GotohDepartment of Applied Chemistry, Yokohama National University, Yokohama, Japan.ORCID https://orcid.org/0000-0002-1920-6020

Funding

Japan Society for the Promotion of Science (JSPS) KAKENHI JP24K08785
6 · The paper itself

Abstract

backgroundAntioxidants can prevent oxidative stress-induced aging and diseases, and many antioxidant screening tests have been conducted in the pharmaceutical and food industries. However, the potencies of antioxidants calculated using standard evaluation methods are thermodynamic values at best and ignore the kinetic aspects of their reactions. In this study, 56 compounds with four basic structures (phenol, methoxyphenol, hydroquinone and catechol) were prepared for Trolox equivalent antioxidant capacity (TEAC) assay and reaction tracking over time. The reaction tracking results were evaluated in terms of the stoichiometric number (n) after 10 s (n

resultsParameter n

conclusionThe radical scavenging ability of antioxidants can be better assessed by conducting evaluations from both thermodynamic and kinetic aspects. This study provides a better understanding of the properties of antioxidants during conventional evaluations using 2,2-diphenyl-1-picrylhydrazyl measurements. © 2025 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

AntioxidantsFree Radical ScavengersPhenolsCatecholsKineticsThermodynamicsAntioxidantscatecholCatecholsFree Radical ScavengersPhenolsantioxidantsantiradical activityDPPHfree radicalphenolic compoundsTrolox equivalent antioxidant capacity

Identifiers

PMID40704663
PMCPMC12509046

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.