Trial reportJournal of the International Society of Sports Nutrition2025
No effects of caffeine on cycling to exhaustion and perceptual responses in non-caffeine-restricted subjects.
Trial report in Journal of the International Society of Sports Nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCaffeine has been shown to improve endurance performance probably primary due to its pharmacological effects in the central nervous system modifying, among others, the perceptual responses during exercise. However, most studies proving the performance-enhancing effects of caffeine utilized an experimental caffeine restriction phase prior to the measurement sessions. Therefore, the effects of 2.5 and 6 mg*kg
methodsTwo double-blinded, randomized placebo-controlled cross-over studies were performed to test the effect of 2.5 (
resultsNeither a dose of 2.5 nor of 6.0 mg*kg
conclusionBoth dosages of caffeine had no effect on TTE, perceived fatigue, perceptual-discriminatory, affective-motivational, and cognitive-evaluative responses to exercise, as well as on time perception and heart rate in low-to-moderate caffeine consumers without a prior experimental caffeine restriction phase. The findings suggest that caffeine´s positive effects on endurance performance and perceptual responses to exercise found in previous studies might be partly explained by the reversal of adverse effects induced by a prior caffeine restriction phase.
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