Evidence map›Paper›PMID 40704341›Full record

ArticleTanaffos2024

Potential Laboratory Markers in COVID-19 Patients with Gastrointestinal Impairments as Prognosticators of the Disease Severity.

Nayebali Ahmadi, Maryam Shahali, Ashkan Alamdary, Alireaza Gholami, Rasul Moukhah, Mohammadjavad Hossein Tehrani, Delaram Doroud, Ariana Alavi, Rajab Mardani

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Tanaffos, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nayebali AhmadiProteomics Research Center, Department of Medical Lab Sciences, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Maryam ShahaliDepartment of Viral Vaccines, Production and Complex Research, Pasteur Institute of Iran, Tehran, Iran.
Ashkan AlamdaryDepartment of Viral Vaccines, Production and Complex Research, Pasteur Institute of Iran, Tehran, Iran.
Alireaza GholamiDepartment of Viral Vaccines, Production and Complex Research, Pasteur Institute of Iran, Tehran, Iran.
Rasul MoukhahDepartment of Quality Assurance, Production and Complex Research, Pasteur Institute of Iran, Tehran, Iran.
Mohammadjavad Hossein TehraniDepartment of Clinical Biochemistry, Hamadan University of Medical Science, Hamadan, Iran.
Delaram DoroudDepartment of Production, Research and Production Complex, Pasteur Institute of Iran.
Ariana AlaviDepartment of Production, Research and Production Complex, Pasteur Institute of Iran.
Rajab MardaniDepartment of Viral Vaccines, Production and Complex Research, Pasteur Institute of Iran, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The new coronavirus infectious disease, COVID-19, is constantly killing people around the world. The main clinical symptoms of COVID-19 include fever, cough, shortness of breath, weakness, fatigue, and sputum/discharge. Gastrointestinal (GI) impairments are often associated with respiratory manifestations in COVID-19 patients. The current study aimed to examine potential laboratory markers in COVID-19 patients with gastrointestinal impairments as prognosticators of disease severity. Materials and Methods: In the present study, hospitalized COVID-19 patients with respiratory symptoms as the main clinical manifestations and gastrointestinal symptoms were studied to evaluate relevant blood biomarkers including vitamins B12, D, and K in addition to albumin, pre-albumin, calcium, and magnesium. Results: Sixty individuals (29 males and 31 females) participated in the study aged between 29 and 72 years, with a mean of 45.87 years. Our results showed a significant increase in albumin, pre-albumin, transferrin, and vitamin K and a significant decrease in magnesium and vitamin B12. Decreases in calcium and vitamin D were modestly associated with the clinical picture of the patient group. Conclusion: Our findings suggest that monitoring laboratory markers such as transferrin, serum albumin, vitamin K, and magnesium-to-calcium ratio could be valuable prognosticators for COVID-19 infection. They could assist in better patient management and disease control.

Indexed as

BiomarkerCOVID-19Respiratory SymptomSARS-CoV-2

Identifiers

PMID40704341
PMCPMC12281346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.