ArticleFrontiers in nutrition2025
The association between a dietary index for the gut microbiota and frailty in older adults: emphasising the mediating role of inflammatory indicators.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Multi-cohort evidence linking edentulism to frailty among older adults.Scientific reports · 2025Pooled it
- Qifuyin improves physiological frailty by regulating the intestinal flora in 3xTg-AD mice.Frontiers in microbiology · 2026Article
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Authors and funding
6 authors.
Funding
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Abstract
Background: The dietary index for the gut microbiota (DI-GM) is a novel indicator of gut microbiome health, and its association with frailty remains unknown. Methods: We recruited participants from the 2007-2020 National Health and Nutrition Examination Survey (NHANES). Restricted cubic splines (RCSs) and multifactorial logistic regression were employed to investigate the relationship between the DI-GM and frailty. A mediation analysis was conducted to evaluate the mediating role of inflammatory markers. Stratification and sensitivity analyses were performed to evaluate the consistency of this association. Results: A total of 4,578 eligible individuals were screened, with a frailty prevalence of 35.50%. After adjusting for all of the covariates, each unit increase in the DI-GM was associated with a 6% decrease in the prevalence of frailty (OR = 0.94; 95% CI: 0.89, 0.99; Conclusion: An elevated DI-GM, which reflects a healthier microbiota state, was associated with a reduced prevalence of frailty. This relationship was partially mediated through inflammatory biomarkers.
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