Evidence map›Paper›PMID 40704265›Full record

ArticleCureus2025

The Overlooked Diagnosis: A Case Report on Autonomic Dysfunction and Chronic Dizziness in an Elderly Patient With Neuroimaging Correlation.

Saran Ak, Tribhuwan Kumar, Md Zabihullah, Gagan K Banodhe, Raihan Mannan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saran AkPhysiology, All India Institute of Medical Sciences, Patna, Patna, IND.
Tribhuwan KumarPhysiology, All India Institute of Medical Sciences, Patna, Patna, IND.
Md ZabihullahPhysiology, All India Institute of Medical Sciences, Patna, Patna, IND.
Gagan K BanodhePhysiology, All India Institute of Medical Sciences, Patna, Patna, IND.
Raihan MannanPhysiology, All India Institute of Medical Sciences, Patna, Patna, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dizziness is a common yet diagnostically challenging complaint in the elderly, often resulting from multifactorial causes such as vestibular dysfunction, autonomic impairment, and cerebrovascular disease. This case report describes a 74-year-old woman with persistent, non-vertiginous dizziness, exacerbated by postural changes, but without orthostatic hypotension or classic vestibular signs. Comprehensive evaluation, including autonomic function tests, tilt-table testing, and neuroimaging, revealed autonomic dysfunction and chronic small-vessel ischemic changes in the periventricular white matter, along with a small hypodense lesion in the pons. Specifically, the patient exhibited reduced heart rate variability, impaired parasympathetic reflexes, and cerebrovascular alterations suggestive of disrupted autonomic pathways. This case underscores the importance of integrating autonomic testing with neuroimaging to elucidate the underlying pathophysiology of chronic dizziness in elderly patients.

Indexed as

autonomic dysfunctionchronic dizzinesselderlyheart rate variabilitysmall vessel ischemiatilt table test

Identifiers

PMID40704265
PMCPMC12285608

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.