Case report: A young woman with acute peri‑myocarditis and acute myeloid leukaemia with myelodysplasia-related changes.

Zsolt Szakács, Tamás Habon, László Kereskai, László Gopcsa, Hussain Alizadeh

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Article in Leukemia research reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Zsolt SzakácsDivision of Hematology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary.

Tamás HabonDivision of Cardiology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary.

László KereskaiDepartment of Pathology, Medical School, University of Pécs, Pécs, Hungary.

László GopcsaSouth-Pest Hospital Centre - National Institute for Infectology and Haematology, Budapest, Hungary.

Hussain AlizadehDivision of Hematology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary.

Funding

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6 · The paper itself

Abstract

Background: Clinical presentation in acute myeloid leukaemia (AML) can result in a wide variety of clinical phenotypes. Case Report: We report the case of a 34-year-old woman who presented with severe peri‑myocarditis and concomitant AML. The patient was treated with 5-azacitidine and venetoclax followed by haploidentical allogenic haematopoetic stem cell transplantation. Unfortunately, the patient developed febrile neutropenia and died because of overwhelming neutropenic sepsis. On autopsy, no evidence of AML was identified neither in bone marrow nor in cardiac tissue. Conclusion: With this case report, we would like to emphasize the possibility of cardiac involvement in AML as well as the potential application of novel therapeutic agents in AML patients unfit for intensive chemotherapy.

Indexed as

Acute myeloid leukaemiaAzacitidineMyocarditisStem cell transplantationVenetoclax

Identifiers

PMID40704103

DOI10.1016/j.lrr.2025.100527

PMCPMC12284280

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