ReviewMaterials today. Bio2025
Recent advances in hydrogel-assisted treatment of malignant bone tumors.
Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Decoding osteosarcoma mechanobiology: PIEZO channels in tumor progression, immune remodeling, and pain.Cancer metastasis reviews · 2026Review
- Liposomal multimodal theranostics for bone disorders: from rational responsive delivery and biomimetic strategies to clinical translation.Journal of nanobiotechnology · 2026Review
- Fundamentals and Advances in Programmable Peptide Hydrogels for Multifunctional Biomedical Applications: A Review.Gels (Basel, Switzerland) · 2026Review
- Recent Advances in Smart Stimulus-Responsive Hydrogels for Precision Drug Delivery in Tumours.Gels (Basel, Switzerland) · 2026Review
- Overcoming barriers in primary bone cancer: Nanomaterial-enabled immunotherapy.Materials today. Bio · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant bone tumors represent a significant risk to human health, manifesting in various forms such as persistent pain, bone defects, joint dysfunction, and other complications. These factors greatly influence the prognosis and life quality of patients. Traditional tumor therapies including surgery, chemotherapy, and radiotherapy, have demonstrated effectiveness in eliminating tumor cells. However, the recurrence of tumors and bone defects caused by tumors continue to present challenges for clinicians. Therefore, there is an urgent need for innovative approaches to address these difficulties. Hydrogels are a class of promising materials with properties close to the extracellular matrix (ECM) and potential for diverse biofunctionalization. With the constant study and development of oncology and regeneration medicine, hydrogels and their composites are developing as novel implants for specialized antitumor and osteogenic treatment. This review aims to present the latest advances in the fabrication of advanced hydrogels with diverse characteristics, as well as their biological mechanisms for the treatment of malignant bone tumors, which includes both the eradication of tumor cells and the promotion of bone regeneration. Additionally, by reviewing the advancements of hydrogel-assisted treatment along with their shortcomings, a perspective will be provided.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.