ArticleFrontiers in radiology2025
Assessing the consistency of CT-based ventilation imaging under noise reduction processing with simulated quantum noise using a nonrigid alveoli phantom.
Article in Frontiers in radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Previous studies have reported that quantum noise inherently present in CT images hinders the generation of CT-based ventilation image (CTVI), while quantum noise reduction approaches that do not affect CTVI have not yet been reported. Aims: The purpose of this study was to evaluate the impact of noise reduction preprocessing on the accuracy and robustness of CTVI in relation to quantum noise present in CT images. Methods and material: To reproduce the quantum noise, Gaussian noise (SD: 30, 80, 150 HU) was added to each inhalation and exhalation CT image. CTVI Statistical analysis used: Cohen's kappa coefficient and Spearman's correlation were used to assess the agreement between CTVI Results: CTVI Conclusions: CNN-based denoising effectively improved the accuracy and robustness of CTVI under quantum noise.
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