Evidence map›Paper›PMID 40703806›Full record

ArticleNeuro-oncology advances

Hyperpolarized

Nicole I C Cappelletto, Hany Soliman, Biranavan Uthayakumar, Arjun Sahgal, Nadia D Bragagnolo, Albert P Chen, Ruby Endre, Nathan Ma, William J Perks, Jay S Detsky and 2 more

Abstract read
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Enhanced Glioblastoma Detection ThroughMagnetic resonance in medicine · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nicole I C CappellettoPhysical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-2181-8093
Hany SolimanRadiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Biranavan UthayakumarPhysical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-9029-4449
Arjun SahgalRadiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Nadia D BragagnoloPhysical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-3399-2267
Albert P ChenGE Healthcare, Taichung, Taiwan.
Ruby EndrePhysical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Nathan MaPharmacy, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
William J PerksPharmacy, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Jay S DetskyRadiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-0117-6839
Chris HeynRadiology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-3226-5199
Charles H CunninghamPhysical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-9636-8130

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Brain metastases (BM) are increasingly treated with stereotactic radiosurgery (SRS); however, up to 30% of BM recur locally. This work investigated whether hyperpolarized (HP) [1- Methods: Eighteen patients with 44 BM were imaged with HP [1- Results: Univariable analysis identified lesion [1- Conclusions: HP lesion [1-

Indexed as

brain metastaseshyperpolarized [1-13C]-pyruvate MRImixed effects logistic regressionstereotactic radiosurgerytreatment response

Identifiers

PMID40703806
PMCPMC12284644

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.