ArticleFrontiers in neurology2025
Non-traditional lipid parameters are independent predictors of the location, distribution, and stroke events of moderate-to-severe intracranial and extracranial atherosclerotic stenosis.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Article
- Association of plasma homocysteine with the atherogenic index of plasma and modification by body mass index: a cross-sectional study.Frontiers in cardiovascular medicine · 2026Article
- Nonlinear relationship between incidence of new-onset stroke and plasma atherosclerotic index in middle-aged and older adults.Frontiers in neurology · 2025Article
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Authors and funding
11 authors.
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Abstract
Objective: Moderate-to-severe stenosis has been identified as a significant risk factor for stroke recently. This study aims to investigate the relationship between non-traditional lipid parameters and the location and distribution of stenosis, as well as symptomatic events, in patients with moderate-to-severe intracranial atherosclerotic stenosis (ICAS) and extracranial atherosclerotic stenosis (ECAS). Methods: This study analyzed correlation between non-traditional lipid parameters and moderate-to-severe ICAS and ECAS concerning stenosis location, distribution, and the presence or absence of symptoms. Logistic models and restricted spline analysis were utilized to explore the relationship between Castelli's risk index-II (CRI-II) and the occurrence of stroke events. Results: The present study comprised 1,030 participants, of whom 143 were non-stenotic and 887 were patients with moderate-to-severe stenosis. The study focuses on the latter and indicated statistically significant differences in AIP, LCI, RC, AC, CRI-I, and CRI-II among the three groups of ICAS, ECAS, and combined ICAS and ECAS (
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