Evidence map›Paper›PMID 40703766›Full record

ArticleAmerican journal of ophthalmology case reports2025

Incidental detection of retinal nerve fiber layer thinning with slowed progression following optic nerve-carotid artery decompression: A case report.

Hidenori Takahashi, Keisuke Ohtani, Takeshi Hara, Kensuke Kawai

Abstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hidenori TakahashiCenter for Cyber Medicine Research, University of Tsukuba, 1-1-1 Tennodai Tsukuba-shi, Ibaraki, Japan.
Keisuke OhtaniDepartment of Neurosurgery, Jichi Medical University, 3311-1 Yakushiji Shimotsuke-shi, Tochigi, Japan.
Takeshi HaraDepartment of Ophthalmology, Jichi Medical University, 3311-1 Yakushiji Shimotsuke-shi, Tochigi, Japan.
Kensuke KawaiDepartment of Neurosurgery, Jichi Medical University, 3311-1 Yakushiji Shimotsuke-shi, Tochigi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This report aims to present a case of the retinal nerve fiber layer (NFL) thinning, in which the progression of thinning was slowed following optic nerve-carotid artery decompression surgery. Observations: A 41-year-old ophthalmologist incidentally noticed a generalized thinning of NFL in his left eye using optical coherence tomography (OCT). Five years earlier, the OCT showed only mild thinning. While visual acuity and visual fields were normal, the patient reported a blurriness. The MRI revealed an ectatic and tortuous left internal carotid artery compressing the left optic nerve. Due to the lack of reports on the correlation between NFL thickness and visual acuity, an internal review was conducted. We searched for cases with a progression from healthy visual acuity to blindness, and in the only case identified, we investigated the correlation between NFL thickness and visual acuity. Applying this correlation, it was predicted that the patient would lose vision by age 48. As a result, the patient decided to receive decompression surgery. Following the surgery, the rate of NFL thinning significantly slowed from -1.9 μm/year to -0.57 μm/year (p < .0001). At the current age of 48, the patient's corrected visual acuity is 20/16, and visual field remains normal. The predicted onset of blindness has been postponed by 10 years. Conclusions and importance: We report a case in which compression of the optic nerve by the internal carotid artery was observed in a patient with retinal nerve fiber layer (NFL) thinning. A slowing of NFL thinning was noted following surgical decompression.

Indexed as

Case reportInternal carotid arteryNeurovascular compressionOptic nerveRetinal nerve fiber layer thinningVascular decompression surgery

Identifiers

PMID40703766
PMCPMC12283895

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.