Evidence map›Paper›PMID 40703663›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2025

Impact of Active Fluidics System on RNFL and GCL in Phacoemulsification.

Alessandra Di Maria, Vanessa Ferraro, Gianmaria Barone, Massimo Vitali, Costanza Tredici, Alessandro Gaeta, Paolo Vinciguerra, Filippo Confalonieri

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alessandra Di MariaDepartment of Ophthalmology, IRCCS Humanitas Research Hospital, Milan, Italy.ORCID 0000-0002-4889-6315
Vanessa FerraroDepartment of Ophthalmology, IRCCS Humanitas Research Hospital, Milan, Italy.
Gianmaria BaroneDepartment of Ophthalmology, IRCCS Humanitas Research Hospital, Milan, Italy.
Massimo VitaliDepartment of Ophthalmology, IRCCS Humanitas Research Hospital, Milan, Italy.
Costanza TrediciDepartment of Ophthalmology, IRCCS Humanitas Research Hospital, Milan, Italy.
Alessandro GaetaDepartment of Internal Medicine and Medical Specialties (DIMI), Università Di Genova, Genova GE, 16132, Italy.
Paolo VinciguerraDepartment of Ophthalmology, IRCCS Humanitas Research Hospital, Milan, Italy.
Filippo ConfalonieriDepartment of Ophthalmology, Montecchi Hospital of Suzzara, Suzzara, 46029, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim of this study was to evaluate whether cataract surgery performed using the Active Fluidics Materials and Methods: Inclusion criteria comprised age-related cataract N4 NC4, BCVA ≤ 0.6, and subjects aged >18 years. Exclusion criteria encompassed glaucoma therapy, anatomical pathologies, or retinal history. Preoperatively, participants underwent comprehensive ophthalmological assessment. Macular GCL and peripapillary RNFL evaluations were conducted using the Heidelberg Spectralis Results: No significant differences were found before and after surgery in GCL. Regarding RNFL thickness, a significant increase was observed in several sectors. Changes in the computerized VF test showed variations, but these were not statistically significant. Conclusion: We found no significant changes in GCL nor retinal function. However, there was an increase in peripapillary RNFL, likely due to underestimation caused by lens opacification before surgery. Overall, the Alcon

Indexed as

cataractganglion cell layerGCLglaucomaphacoemulsificationretinal nerve fiber layerRNFL

Identifiers

PMID40703663
PMCPMC12283234

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.