Evidence map›Paper›PMID 40703653›Full record

ArticleFrontiers in cell and developmental biology2025

Itpka depletion implicates defects in anterior neural development of

Ernestine Saumweber, Marie-Christine Becker, Sophie Kunkel, Jana Welke, Sandra Schott, Christian Vizinho-Vieira, Selina Faoual, Michael J Schmeisser, Susanne J Kühl

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ernestine Saumweber *Institute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany.
Marie-Christine Becker *Institute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany.
Sophie KunkelInstitute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany.
Jana WelkeInstitute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany.
Sandra SchottInstitute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany.
Christian Vizinho-VieiraInstitute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany.
Selina FaoualInstitute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany.
Michael J Schmeisser *Institute of Anatomy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Susanne J Kühl *Institute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inositol 1,4,5-trisphosphate 3-kinase A (Itpka) is a neuronal isoform of the ITPK family that regulates both actin dynamics and calcium signaling. While

Indexed as

anterior neural developmentdisease modelingembryogenesisITPKAXenopus laevis

Identifiers

PMID40703653
PMCPMC12283734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.