Evidence map›Paper›PMID 40703631›Full record

ArticleFrontiers in cardiovascular medicine2025

Association between obesity and cardiac conduction defects.

Mohamed A Mostafa, Jeff A Kingsley, Elsayed Z Soliman, Prashant D Bhave

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohamed A Mostafa *Department of Cardiovascular medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Jeff A Kingsley *Department of Cardiovascular medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Elsayed Z SolimanDepartment of Cardiovascular medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Prashant D BhaveDepartment of Cardiovascular medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Literature on the association between high body mass index (BMI) and cardiac conduction defects (CCD) is scarce. Methods: The cross-sectional association between obesity and CCD was examined in 455,790 participants (56.1 years; 55.9% females) from the United Kingdom (UK) Biobank. CCD was defined by ICD codes as the presence of either atrioventricular block (AVB) or intraventricular block (IVB). Multivariable logistic regression models were used to assess the association between different levels of BMI and CCD. Results: About 2.7% ( Conclusions: Higher BMI levels are associated with an increased risk of CCD, which is probably triggered by AVB, and the association is stronger in men, the elderly, and those with diabetes; further research is needed to examine whether weight management in obesity will be accompanied by a reduction in the risk of CCD.

Indexed as

BMIcardiac conduction defectsheart blockobesityUK biobank

Identifiers

PMID40703631
PMCPMC12284001

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.