ArticleJournal of oral biology and craniofacial research
Biological effects of two nano-composite resins on human gingival fibroblast (an
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Comparative analysis of chemical properties and biocompatibility among high ceramic filler-based 3D printed resins, low filler-based 3D printed resins and CAD/CAM ceramics.Clinical oral investigations · 2026Article
- Evaluation of the total antioxidant capacity and cytotoxicity of single shade universal resin composites.BMC oral health · 2025Article
- Surgical Free Gingival Root Coverage Graft Embedded in a Modified Subperiosteal Flap: A Novel Case Report.Case reports in dentistry · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To elucidate the genotoxic and cytotoxic effects of two different nano-composite resins on primary human gingival fibroblasts (HGFs). Methods: The HGFs were isolated, characterized, and classified into 3 groups. The control group consisted of untreated HGFs, the Omnichroma extract treated HGFs (the OMN group), and the 3M Filtek Z350 xt extract treated HGFs (ESPE group). The cell viability, mode of cell death and expression of Results: The isolated HGFs were characterized. The HGF viability was significantly higher in the OMN groups than ESPE groups at most of the concentrations. Total cell death was higher in the ESPE groups and at the OMN group at 72 h in comparison to the control and was higher in the ESPE groups compared to OMN groups. Furthermore, the Conclusion: The cytotoxic and genotoxic effect of ESPE on HGF is more significant than the OMN.
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Registered trials
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