Evidence map›Paper›PMID 40703426›Full record

ReviewJSES international2025

Clinical outcomes following intramedullary nailing of humerus fractures: a systematic review.

Kwabena Adu-Kwarteng, Eoghan T Hurley, Kiera Lunn, Jessica M Welch, Tom R Doyle, Jay M Levin, Oke Anakwenze, Yaw D Boachie-Adjei, Christopher S Klifto

Abstract readReview
In one paragraph

Review in JSES international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kwabena Adu-KwartengSchool of Medicine, Duke University, Durham, NC, USA.
Eoghan T HurleyDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
Kiera LunnSchool of Medicine, Duke University, Durham, NC, USA.
Jessica M WelchSchool of Medicine, Duke University, Durham, NC, USA.
Tom R DoyleDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
Jay M LevinDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
Oke AnakwenzeDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
Yaw D Boachie-AdjeiDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
Christopher S KliftoDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The purpose of this study is to systematically review the literature to assess clinical outcomes arising from intramedullary nailing (IMN) of humerus fractures. Methods: Two independent reviewers performed a literature search in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Studies were included if they reported on patient-reported outcomes and range of motion following the use of IMN for humerus fractures between 2000 and 2023. Results: A total of 88 studies, including 4255 patients, met the inclusion criteria for review. The majority of patients were female, with a mean age of 58.3 ± 12.4 years and a mean follow-up of 21.2 ± 15.2 months. The primary outcome score utilized for postoperative assessment was the Constant-Murley Score (CMS). The mean CMS for all fractures, proximal humerus fractures (PHFs), and humeral shaft fractures were 74.7 ± 12.5, 74.2 ± 12.3, and 77.3 ± 12.1, respectively. The mean CMS in 2-part, 3-part, and 4-part PHFs was 80.8 ± 8.8, 80.4 ± 12.3, and 66.5 ± 11.3, respectively. The primary range of motion measurements measured for postoperative assessment were forward flexion and external rotation. The mean forward flexion for all fractures, PHFs, and humeral shaft fractures was 135° ± 16°, 131° ± 13°, and 143° ± 18°, respectively. The mean external rotation for all fractures, PHFs, and humeral shaft fractures was 46° ± 15°, 43° ± 13°, and 52° ± 16°, respectively. Conclusion: IMN for humerus fractures provides good functional outcomes in both proximal humerus and humeral shaft fractures. However, functional outcomes in PHFs decreased as the number of displaced fracture parts increased.

Indexed as

FractureHumeral shaftHumerusIntramedullaryNailProximal humerus

Identifiers

PMID40703426
PMCPMC12281184

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.