Evidence map›Paper›PMID 40703359›Full record

ReviewFrontiers in pharmacology2025

Yunnan Baiyao (YNBY): pharmacological mechanisms, therapeutic applications, and clinical evidence.

Hongjing Qian, Wanli Zhang, Mingzhu Zhang, Sijia Ma, Manhong Zhen, Hongbing He, Xiaobin Ren

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hongjing QianYunnan Key Laboratory of Stomatology, School of Stomatology, Kunming Medical University, Kunming, China.
Wanli ZhangYunnan Key Laboratory of Stomatology, School of Stomatology, Kunming Medical University, Kunming, China.
Mingzhu ZhangYunnan Key Laboratory of Stomatology, School of Stomatology, Kunming Medical University, Kunming, China.
Sijia MaYunnan Key Laboratory of Stomatology, School of Stomatology, Kunming Medical University, Kunming, China.
Manhong ZhenYunnan Key Laboratory of Stomatology, School of Stomatology, Kunming Medical University, Kunming, China.
Hongbing HeYunnan Key Laboratory of Stomatology, School of Stomatology, Kunming Medical University, Kunming, China.
Xiaobin RenYunnan Key Laboratory of Stomatology, School of Stomatology, Kunming Medical University, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Yunnan Baiyao (YNBY) is a traditional Chinese medicine widely used in hemostasis, anti-inflammation, antibacterial, analgesia and wound healing. This article reviews the research progress on the pharmacological mechanism, clinical application and safety of YNBY in the past two decades. Through systematic analysis of clinical trials, animal experiments and mechanistic studies, YNBY has shown significant effects in reducing surgical bleeding (such as reducing blood loss in orthognathic surgery by 21.4%), accelerating wound healing (such as increasing the healing rate of diabetic ulcers by 37%), regulating inflammation (such as inhibiting the expression of IL-6/CRP in arthritis), and inhibiting bacterial virulence (such as destroying

Indexed as

botanical drugclinical applicationhemostatic efficacytraditional Chinese medicineYunnan Baiyao

Identifiers

PMID40703359
PMCPMC12284948

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.