ArticleFrontiers in medicine2025
No difference in endothelial microvasculation measured by peripheral arterial tonometry in patients with Sjögren's disease and matched controls.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Sjögren's disease (SjD) is a connective tissue autoimmune disorder characterized by inflammatory infiltration of the exocrine glands, leading to symptoms such as dryness, pain, and fatigue. Additionally, up to 50% of patients may experience extraglandular manifestations. SjD patients face a higher cardiovascular risk, including severe events like myocardial infarction and strokes, partly due to an increased likelihood of subclinical atherosclerosis. Therefore, identifying SjD patients at an early stage is essential to reduce morbidity and mortality. In this study, SjD patients who met the current ACR/EULAR 2016 classification criteria were consecutively enrolled in our outpatient clinic. A control cohort was recruited through a multimedia call for participation. To assess changes in endothelial functions, a reactive hyperemia index (RHI) was calculated using peripheral arterial tonometry with the EndoPAT
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