ReviewFrontiers in microbiology2025
Nanomedicine in fungal keratitis: current applications and future prospects.
Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Bridging the "Valley of Death" in Antifungal Therapy: Next-Generation Biomimetic and Exosome-Inspired Nanocarriers for Invasive Candidiasis.Journal of fungi (Basel, Switzerland) · 2026Review
- Anti-Scientifica · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fungal keratitis (FK) poses a significant public health challenge, causing substantial harm to human health and the socio-economic landscape. However, due to the special anatomical and physiological characteristics of the eye, the current therapeutic drugs for FK are not effective, which brings obstacles to the clinical treatment of FK. Nanomedicine is a new therapeutic method that has emerged in the field of FK therapy in recent years. On the one hand, nanomaterials can directly kill fungi by separating ions, and on the other hand, the drug delivery system (DDS) composed of nanomaterials can target and deliver traditional drugs to the affected area and play a bactericidal role, with a significantly higher effect than traditional therapy. This review begins with a bibliometric analysis of research progress in FK nanomedicine. Then we describe the mechanism and effect of various nanomedicine in the treatment of FK from the perspective of direct and indirect treatment, focusing on the attack of nanomedicine on biofilm and DDS composed of nanomaterials. Finally, this field is prospected in order to provide new insights and ideas for the development of FK nanomedicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.