Evidence map›Paper›PMID 40703235›Full record

ArticleFrontiers in microbiology2025

Unraveling the microbiome-aroma Nexus: a metagenomic and volatile compound analysis of Yunnan cigars.

Jing Pan, Ming-Da Huang, Jin Wang, Jian-Xiong Zhao, Bin Yang, Hong-Hui Yang, Jin-Sheng Huang, Yu-Long Su, Xue-Ru Song, Wei-Guang Wang and 1 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jing PanKey Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal Endophytes, State Ethnic Affairs Commission, Key Laboratory of Chemistry in Ethnic Medicinal Resources, Ministry of Education, Yunnan Minzu University, Kunming, China.
Ming-Da HuangKey Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal Endophytes, State Ethnic Affairs Commission, Key Laboratory of Chemistry in Ethnic Medicinal Resources, Ministry of Education, Yunnan Minzu University, Kunming, China.
Jin WangYunnan Key Laboratory of Tobacco Chemistry, China Tobacco Yunnan Industrial Co., Ltd., Kunming, China.
Jian-Xiong ZhaoYunnan Tobacco Company, Lincang Branch, Lincang, China.
Bin YangYunnan Tobacco Company, Lincang Branch, Lincang, China.
Hong-Hui YangYunnan Tobacco Company, Lincang Branch, Lincang, China.
Jin-Sheng HuangYunnan Tobacco Company, Lincang Branch, Lincang, China.
Yu-Long SuYunnan Tobacco Company, Yuxi Branch, Yuxi, China.
Xue-Ru SongYunnan Tobacco Company, Yuxi Branch, Yuxi, China.
Wei-Guang WangKey Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal Endophytes, State Ethnic Affairs Commission, Key Laboratory of Chemistry in Ethnic Medicinal Resources, Ministry of Education, Yunnan Minzu University, Kunming, China.
Ling-Duo BuYunnan Tobacco Company, Yuxi Branch, Yuxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Understanding how microbial communities influence aroma profiles is critical to improving cigar quality. However, comparative studies examining the microbiome-aroma nexus across major cigar-producing regions remain limited. Methods: We integrated high-throughput metagenomic sequencing with volatile organic compound (VOC) profiling to investigate microbial community structure and aroma compounds in four Yunnan cigars and two Cuban cigars. Results: Discussion: Our findings demonstrate that region-specific fermentation microbiota are intricately linked to the production of key VOCs. This work provides a scientific framework for optimizing cigar fermentation through microbial regulation and supports the potential for targeted microbial inoculation to enhance sensory quality and global competitiveness.

Indexed as

cigarmetagenomicmicrobial communitymicrobial metabolismmicrobiomevolatile organic compounds

Identifiers

PMID40703235
PMCPMC12283659

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.