Evidence map›Paper›PMID 40703225›Full record

ArticleBrain, behavior, & immunity - health2025

Peer victimization in adolescence alters gene expression and cytokine profiles during transition to adulthood.

Jens Heumann, Steve W Cole, Manuel Eisner, Denis Ribeaud, Edna Grünblatt, Michael J Shanahan

Abstract read
In one paragraph

Article in Brain, behavior, & immunity - health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jens HeumannJacobs Center for Productive Youth Development, University of Zurich, 8050, Zurich, Switzerland.
Steve W ColeDepartments of Psychiatry and Biobehavioral Sciences and Medicine, Division of Hematology-Oncology, University of California Los Angeles, USA.
Manuel EisnerJacobs Center for Productive Youth Development, University of Zurich, 8050, Zurich, Switzerland.
Denis RibeaudJacobs Center for Productive Youth Development, University of Zurich, 8050, Zurich, Switzerland.
Edna GrünblattDepartment of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital Zurich, University of Zurich, 8032, Zurich, Switzerland.
Michael J ShanahanJacobs Center for Productive Youth Development, University of Zurich, 8050, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adolescents who experience peer victimization (PV) often report psychosomatic complaints; however, little is known about possible underlying molecular effects. Social adversity has already been shown to downregulate immune genes and upregulate inflammatory genes. This study investigated PV for potentially enduring molecular effects, in terms of gene expression, leukocyte composition, and cytokine levels in young adulthood. Participants (

Indexed as

CounterfactualCytokinesGene expressionIn silico deconvolutionLeukocytesLife coursePeer victimizationReactome pathwaysTranscription factors

Identifiers

PMID40703225
PMCPMC12284792

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.