Evidence map›Paper›PMID 40703202›Full record

ArticleNeurology. Genetics2025

Executive Function Deficits in Genetic Frontotemporal Dementia: Results From the GENFI Study.

Lucy Louise Russell, Arabella Bouzigues, Rhian S Convery, Phoebe H Foster, Eve Ferry-Bolder, David M Cash, John C Van Swieten, Lize Corrine Jiskoot, Harro Seelaar, Fermin Moreno and 23 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology. Genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Lucy Louise RussellDepartment of Neurodegenerative Disease, Dementia Research Centre, UCL Institute of Neurology, London, United Kingdom.ORCID https://orcid.org/0000-0001-5023-5893
Arabella BouziguesDepartment of Neurodegenerative Disease, Dementia Research Centre, UCL Institute of Neurology, London, United Kingdom.ORCID https://orcid.org/0000-0002-0267-8590
Rhian S ConveryDepartment of Neurodegenerative Disease, Dementia Research Centre, UCL Institute of Neurology, London, United Kingdom.ORCID https://orcid.org/0000-0002-9477-1812
Phoebe H FosterDepartment of Neurodegenerative Disease, Dementia Research Centre, UCL Institute of Neurology, London, United Kingdom.ORCID https://orcid.org/0000-0001-6300-6598
Eve Ferry-BolderDepartment of Neurodegenerative Disease, Dementia Research Centre, UCL Institute of Neurology, London, United Kingdom.ORCID https://orcid.org/0009-0006-5083-0901
David M CashDepartment of Neurodegenerative Disease, Dementia Research Centre, UCL Institute of Neurology, London, United Kingdom.ORCID https://orcid.org/0000-0001-7833-616X
John C Van SwietenDepartment of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands.ORCID https://orcid.org/0000-0001-6278-6844
Lize Corrine JiskootDepartment of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands.ORCID https://orcid.org/0000-0002-1120-1858
Harro SeelaarDepartment of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands.ORCID https://orcid.org/0000-0003-1989-7527
Fermin MorenoCognitive Disorders Unit, Department of Neurology, Donostia University Hospital, San Sebastian, Gipuzkoa, Spain.ORCID https://orcid.org/0000-0001-5200-3164
Raquel Sánchez-ValleAlzheimer's disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacións Biomèdiques August Pi I Sunyer, University of Barcelona, Spain.ORCID https://orcid.org/0000-0001-7750-896X
Robert LaforceDépartement des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Clinique Interdisciplinaire de Mémoire, Université Laval, Canada.ORCID https://orcid.org/0000-0002-2031-490X
Caroline GraffCenter for Alzheimer Research, Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Bioclinicum, Karolinska Institutet, Solna, Sweden.ORCID https://orcid.org/0000-0002-9949-2951
Mario MasellisSunnybrook Health Sciences Centre, Sunnybrook Research Institute, University of Toronto, Canada.ORCID https://orcid.org/0000-0002-6244-2096
Maria Carmela TartagliaTanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Canada.ORCID https://orcid.org/0000-0002-5944-8497
James B RoweDepartment of Clinical Neurosciences and Cambridge University Hospitals NHS Trust and Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, United Kingdom.ORCID https://orcid.org/0000-0001-7216-8679
Barbara BorroniCentre for Neurodegenerative Disorders, Department of Clinical and Experimental Sciences, University of Brescia, Italy.ORCID https://orcid.org/0000-0001-9340-9814
Elizabeth FingerDepartment of Clinical Neurological Sciences, University of Western Ontario, London, Canada.ORCID https://orcid.org/0000-0003-4461-7427
Matthis SynofzikDepartment of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany.ORCID https://orcid.org/0000-0002-2280-7273
Daniela GalimbertiDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Italy.ORCID https://orcid.org/0000-0002-9284-5953
Rik VandenbergheLaboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Belgium.ORCID https://orcid.org/0000-0001-6237-2502
Alexandre de MendonçaFaculty of Medicine, University of Lisbon, Portugal.ORCID https://orcid.org/0000-0002-0488-1453
Christopher ButlerNuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, United Kingdom.ORCID https://orcid.org/0000-0002-7502-9284
Alexander GerhardDivision of Psychology Communication and Human Neuroscience Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom.ORCID https://orcid.org/0000-0002-8071-6062
Simon DucharmeDepartment of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, Canada.ORCID https://orcid.org/0000-0002-7309-1113
Isabelle Le BerParis Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225, AP-HP-Hôpital Pitié-Salpêtrière (DMU Neurosciences Paris 6), Sorbonne Université, France.ORCID https://orcid.org/0000-0002-2508-5181
Isabel SantanaNeurology Department, Centro Hospitalar e Universitário de Coimbra, Portugal.ORCID https://orcid.org/0000-0002-8114-9434
Florence PasquierUniv Lille, France.ORCID https://orcid.org/0000-0001-9880-9788
Johannes LevinNeurologische Klinik und Poliklinik, Ludwig-Maximilians-Universität, Munich, Germany.ORCID https://orcid.org/0000-0001-5092-4306
Sandro SorbiDepartment of Neurofarba, University of Florence, Italy.ORCID https://orcid.org/0000-0002-0380-6670
Markus OttoDepartment of Neurology, University of Ulm, German.ORCID https://orcid.org/0000-0003-4273-4267
Jonathan Daniel RohrerDepartment of Neurodegenerative Disease, Dementia Research Centre, UCL Institute of Neurology, London, United Kingdom.ORCID https://orcid.org/0000-0002-6155-8417
Genetic FTD Initiative (GENFI)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Executive dysfunction is a core feature of frontotemporal dementia (FTD). While there has been extensive research into such impairments in sporadic FTD, there has been little research in the familial forms. Methods: Seven hundred fifty-two individuals were recruited in total: 214 Results: Fully symptomatic Discussion: Some individuals with

Identifiers

PMID40703202
PMCPMC12285671

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.