Evidence map›Paper›PMID 40703155›Full record

ReviewFrontiers in public health2025

Principles of environmental medicine: an educational case study of lead poisoning in Beethoven.

Thomas C Erren, Florian Glenewinkel, Andreas Pinger, Philip Lewis

Abstract readHistorical ArticleReview
In one paragraph

Review in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas C ErrenInstitute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
Florian GlenewinkelInstitute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
Andreas PingerInstitute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
Philip LewisInstitute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Understanding the nature and consequences of widespread lead poisoning is critical to protecting people from harm. Educational case study: We review the historical example of hypothesized lead poisoning in the famous composer Beethoven as an educational vector to illustrate principles of environmental medicine. We discuss what would happen if a hypothetical present-day Mr. B with comparable health complaints, clinical symptoms, or test results were to visit a doctor today. Human biomonitoring - with population reference values and health-based guidance values - is discussed as an important diagnostic tool. Conclusion: This practical outlook on lead poisoning for readers with non-environmental medicine backgrounds contributes to an understanding of principles of environmental medicine.

Indexed as

Environmental MedicineLead PoisoningBiological MonitoringEnvironmental ExposureFamous PersonsHumansLeadLeadeducationenvironmenthuman biomonitoringLead poisoningprevention

Identifiers

PMID40703155
PMCPMC12283720

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.