Evidence map›Paper›PMID 40703093›Full record

ArticlePhysics and imaging in radiation oncology2025

Comparison of stereotactic photon and proton treatment plans for metastasis-directed radiotherapy.

Rans Kato, De Roover Robin, De Meerleer Gert, Haustermans Karin, Berghen Charlien, Poels Kenneth

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physics and imaging in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rans KatoDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
De Roover RobinDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
De Meerleer GertDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
Haustermans KarinDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
Berghen CharlienDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
Poels KennethDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Achieving optimal local control is pivotal in the context of metastasis-directed therapy (MDT) in delaying further metastatic spread. The clear correlation between the biological equivalent dose (BED) and local control, with rates reaching 99 % when BED exceeds 100 Gy using an α:β ratio of 3, underlines the importance of investigating advanced radiation modalities. Materials & methods: A planning study was conducted in 20 patients treated for 38 lesions to compare photon based and proton based stereotactic radiation therapy in oligoprogressive metastatic castration-refractory prostate cancer patients. The primary objective was to determine whether proton therapy is achieving a satisfactory BED Results: Volumetric Modulated Arc Therapy (VMAT) and Intensity Modulated Proton Therapy (IMPT) achieved a satisfactory BED Conclusion: Proton therapy may reduce long-term treatment-related toxicities and be more effective for re-irradiation. It achieves a satisfactory BED

Indexed as

Intensity modulated proton therapyMetastasis-directed therapyProgressive-directed therapyProstate cancerStereotactic body radiation therapyVolumetric modulated arc therapy

Identifiers

PMID40703093
PMCPMC12284363

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.