ArticleRSC advances2025
One pot access to 2-iodo-2-deoxy nucleosides directly from glycals and unprotected nucleobases and their biological evaluation on the Japanese Encephalitis Virus.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
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Abstract
An expedient one-pot stereo- and regioselective synthesis of 2-iodo-nucleosides from protected glycals and nucleobases using easily available iodine and hexamethyldisilane as halogenating, and silylating agents respectively has been developed. Most of the products synthesized characterized as diastereomerically pure β-1,2-trans-diequitorial nucleosides hitherto not reported. The
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